(19)
(11) EP 2 633 066 A1

(12)

(43) Date of publication:
04.09.2013 Bulletin 2013/36

(21) Application number: 11836900.8

(22) Date of filing: 21.10.2011
(51) International Patent Classification (IPC): 
C12Q 1/37(2006.01)
(86) International application number:
PCT/US2011/057359
(87) International publication number:
WO 2012/058117 (03.05.2012 Gazette 2012/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 27.10.2010 US 407289 P
27.10.2010 US 407234 P

(71) Applicant: Merck Sharp & Dohme Corp.
Rahway, NJ 07065-0907 (US)

(72) Inventors:
  • HAYASHI, Ikuo
    Pennsylvania 19486 (US)
  • MAJERCAK, John
    Pennsylvania 19486 (US)
  • SHAH, Sanjiv
    Boston, Massachusetts 02115-5727 (US)

(74) Representative: Horgan, James Michael Frederic et al
Merck & Co., Inc. European Patent Department Hertford Road
Hoddesdon Hertfordshire EN11 9BU
Hoddesdon Hertfordshire EN11 9BU (GB)

   


(54) METHODS FOR IDENTIFYING NOTCH-SPARING GAMMA SECRETASE INHIBITORS