(19)

(11)

EP 2 640 749 A1

(12)

(43) Date of publication: 25.09.2013 Bulletin 2013/39 (21) Application number: 11781571.2 (22) Date of filing: 14.11.2011

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) (86) International application number: PCT/EP2011/070058 (87) International publication number: WO 2012/065950 (24.05.2012 Gazette 2012/21)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 15.11.2010 US 413567 P (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventors: HEUSSER, Christoph CH-4056 Basel (CH) RUSH, James CH-4056 Basel (CH) VINCENT, Karen CH-4056 Basel (CH) (74) Representative: Fredh, Fredrik  Novartis Pharma AG Patent Department Postfach 4002 Basel 4002 Basel (CH)