(19)

(11)

EP 2 642 982 A2

(12)

(88) Date of publication A3: 09.08.2012 (43) Date of publication: 02.10.2013 Bulletin 2013/40 (21) Application number: 11791403.6 (22) Date of filing: 22.11.2011

(51) International Patent Classification (IPC):  A61K 9/48(2006.01) A61K 47/10(2006.01) A61K 47/44(2006.01) A61K 31/352(2006.01) A61K 47/12(2006.01) (86) International application number: PCT/US2011/061803 (87) International publication number: WO 2012/071389 (31.05.2012 Gazette 2012/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 22.11.2010 US 416110 P (71) Applicant: Johnson Matthey Public Limited Company London EC4A 4AB (GB)	(72) Inventors: ROSSI, Ronald Mullica Hill, NJ 08062 (US) SILVERBERG, Lee, Jonathan Cherry Hill, NJ 08034 (US) HOGAN, Robert West Grove, PA 19390 (US) SHAH, Ramesh, M. Voorhees, NJ 08043 (US) (74) Representative: Whitcombe, Nicole Jane  Johnson Matthey PLC Gate 20 Orchard Road Royston Hertfordshire SG8 5HE Royston Hertfordshire SG8 5HE (GB)