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(11)

EP 2 643 310 A1

(12)

(43) Date of publication: 02.10.2013 Bulletin 2013/40 (21) Application number: 11802149.2 (22) Date of filing: 09.11.2011

(51) International Patent Classification (IPC):  C07D 401/04(2006.01) C07D 403/14(2006.01) A61K 31/506(2006.01) C07D 401/14(2006.01) A61K 31/454(2006.01) A61P 3/10(2006.01) (86) International application number: PCT/IB2011/054996 (87) International publication number: WO 2012/069948 (31.05.2012 Gazette 2012/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 23.11.2010 US 416441 P (71) Applicant: Pfizer Inc. New York, NY 10017 (US)	(72) Inventors: MASCITTI, Vincent Groton, Connecticut 06340 (US) MCCLURE, Kim Francis Cambridge, Massachusetts 02140 (US) MUNCHHOF, Michael John Salem, Connecticut 06420 (US) ROBINSON, Ralph Pelton, Jr. Groton, Connecticut 06340 (US) (74) Representative: Pfizer  European Patent Department 23-25 avenue du Docteur Lannelongue 75668 Paris Cedex 14 75668 Paris Cedex 14 (FR)