(19)

(11)

EP 2 651 438 A1

(12)

(43) Date of publication: 23.10.2013 Bulletin 2013/43 (21) Application number: 11807964.9 (22) Date of filing: 13.12.2011

(51) International Patent Classification (IPC):  A61K 39/05(2006.01) (86) International application number: PCT/GB2011/001716 (87) International publication number: WO 2012/080696 (21.06.2012 Gazette 2012/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 13.12.2010 GB 201021096 (71) Applicant: Moredun Research Institute Bush Loan Penicuik EH16 0PZ (GB)	(72) Inventors: FONTAINE, Michael Bush Loan Edinburgh EH26 0PZ (GB) WALKER, Caray Cambridge CB1 1PT (GB) (74) Representative: Gibbs, Richard et al Marks & Clerk LLP Atholl Exchange 6 Canning Street Edinburgh EH3 8EG Edinburgh EH3 8EG (GB)