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(11)

EP 2 651 885 A1

(12)

(43) Date of publication: 23.10.2013 Bulletin 2013/43 (21) Application number: 11806100.1 (22) Date of filing: 16.12.2011

(51) International Patent Classification (IPC):  C07D 207/16(2006.01) A61K 31/4025(2006.01) A61K 31/4439(2006.01) C07D 403/04(2006.01) A61K 31/4184(2006.01) A61P 31/12(2006.01) (86) International application number: PCT/US2011/065501 (87) International publication number: WO 2012/083170 (21.06.2012 Gazette 2012/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 16.12.2010 US 423906 P (71) Applicant: Abbvie Inc. North Chicago, IL 60064 (US)	(72) Inventors: KRUEGER, Allan, C. Gurnee Illinois 60031 (US) KATI, Warren, M. Gurnee Illinois 60031 (US) CARROLL, William, A. Evanston Illinois 60201 (US) PRATT, John, K. Kenosha Wisconsin 53142 (US) HUTCHINSON, Douglas, K. Newtown CT 06470-2787 (US) (74) Representative: Modiano, Micaela Nadia  Modiano & Partners (DE) Thierschstrasse 11 80538 München 80538 München (DE)