(19)

(11)

EP 2 655 599 A2

(12)

(88) Date of publication A3: 06.12.2012 (43) Date of publication: 30.10.2013 Bulletin 2013/44 (21) Application number: 11850766.4 (22) Date of filing: 20.12.2011

(51) International Patent Classification (IPC):  C12N 1/21(2006.01) C12P 7/16(2006.01) C12N 15/52(2006.01) C12N 5/10(2006.01) C12N 15/63(2006.01) C12N 9/00(2006.01) (86) International application number: PCT/US2011/066090 (87) International publication number: WO 2012/088071 (28.06.2012 Gazette 2012/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 22.12.2010 US 201061426147 P 29.03.2011 US 201113075153 (71) Applicant: Lee, James Weifu Cockeysville, MD 21030 (US)	(72) Inventor: Lee, James Weifu Cockeysville, MD 21030 (US) (74) Representative: Phillips & Leigh  5 Pemberton Row London EC4A 3BA London EC4A 3BA (GB)