FUSION OF PEPTIDOGLYCAN HYDROLASE ENZYMES TO A PROTEIN TRANSDUCTION DOMAIN ALLOWS ERADICATION OF BOTH EXTRACELLULAR AND INTRACELLULAR GRAM POSITIVE PATHOGENS - Patent 2661495

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EP 2 661 495 A1

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(43)	Date of publication:
	13.11.2013 Bulletin 2013/46

(21)	Application number: 11854973.2

(22)	Date of filing: 05.01.2011

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International Patent Classification (IPC):

C12N 15/62^(2006.01)
C07K 19/00^(2006.01)
C12R 1/445^(2006.01)

C12N 15/55^(2006.01)
A61K 38/43^(2006.01)

(86)	International application number:
	PCT/US2011/020230

(87)	International publication number:
	WO 2012/094004 (12.07.2012 Gazette 2012/28)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(71)	Applicant: The United States of America, as represented by the Secretary of Agriculture
	Washington, DC 20250-0302 (US)

(72)	Inventor:
	DONOVAN, David, M. Baltimore MD 21221 (US)

(74)	Representative: Chas. Hude A/S
	H.C. Andersens Boulevard 33 1780 Copenhagen V 1780 Copenhagen V (DK)

(54)	FUSION OF PEPTIDOGLYCAN HYDROLASE ENZYMES TO A PROTEIN TRANSDUCTION DOMAIN ALLOWS ERADICATION OF BOTH EXTRACELLULAR AND INTRACELLULAR GRAM POSITIVE PATHOGENS