(19)
(11) EP 2 661 506 A2

(12)

(43) Date of publication:
13.11.2013 Bulletin 2013/46

(21) Application number: 12731967.1

(22) Date of filing: 06.01.2012
(51) International Patent Classification (IPC): 
C12Q 1/68(2006.01)
(86) International application number:
PCT/US2012/020564
(87) International publication number:
WO 2012/094651 (12.07.2012 Gazette 2012/28)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 26.08.2011 US 201161527916 P
06.01.2011 US 201161430462 P
08.11.2011 US 201161557203 P
26.08.2011 US 201161527890 P

(71) Applicants:
  • The Board of Trustees of the University of Illinois
    Urbana, Illinois 61801 (US)
  • The United States Government as represented by The Department of Veterans Affairs
    Washington, DC 20420 (US)

(72) Inventor:
  • DUDLEY, Samuel
    Chicago, IL 60611 (US)

(74) Representative: Potter Clarkson LLP 
The Belgrave Centre Talbot Street
Nottingham NG1 5GG
Nottingham NG1 5GG (GB)

   


(54) SCN5A SPLICE VARIANTS FOR USE IN METHODS RELATING TO SUDDEN CARDIAC DEATH AND NEED FOR IMPLANTED CADIAC DEFIBRILLATORS