(19)

(11)

EP 2 667 861 A2

(12)

(88) Date of publication A3: 20.09.2012 (43) Date of publication: 04.12.2013 Bulletin 2013/49 (21) Application number: 12739786.7 (22) Date of filing: 23.01.2012

(51) International Patent Classification (IPC):  A61K 9/70(2006.01) A61P 11/00(2006.01) A61K 47/30(2006.01) (86) International application number: PCT/US2012/022233 (87) International publication number: WO 2012/103016 (02.08.2012 Gazette 2012/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 26.01.2011 US 201161436489 P (71) Applicant: CSI GmbH 73614 Schorndorf (DE)	(72) Inventors: CALDWELL, Larry J. San Jose California 95124 (US) SHIRAI, Sadanobu Takamatsu-shi Kagawa 761-8075 (JP) (74) Representative: Maiwald Patentanwalts GmbH  Elisenhof Elisenstrasse 3 80335 München 80335 München (DE)