(19)
(11) EP 2 670 393 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
05.10.2016 Bulletin 2016/40

(45) Mention of the grant of the patent:
10.08.2016 Bulletin 2016/32

(21) Application number: 12701899.2

(22) Date of filing: 31.01.2012
(51) International Patent Classification (IPC): 
A61K 41/00(2006.01)
A61K 49/18(2006.01)
A61K 31/704(2006.01)
A61K 9/127(2006.01)
A61K 9/51(2006.01)
(86) International application number:
PCT/EP2012/051510
(87) International publication number:
WO 2012/104277 (09.08.2012 Gazette 2012/32)

(54)

METHOD OF MONITORING THE RELEASE FROM LIPOSOMES OF A PRODUCT OF INTEREST USING SUPERPARAMAGNETIC NANOPARTICLES.

VERFAHREN ZUR ÜBERWACHUNG DER FREISETZUNG VON LIPOSOMEN AUS EINEM PRODUKT VON INTERESSE MITHILFE SUPERPARAMAGNETISCHER NANOPARTIKEL

PROCÉDÉ DE SURVEILLANCE DE LA LIBÉRATION PAR DES LIPOSOMES D'UN PRODUIT D'INTÉRÊT AU MOYEN DE NANOPARTICULES SUPERPARAMAGNÉTIQUES


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 31.01.2011 EP 11305097
31.01.2011 US 201161437831 P

(43) Date of publication of application:
11.12.2013 Bulletin 2013/50

(73) Proprietors:
  • Nanobiotix
    75012 Paris (FR)
  • Centre National de la Recherche Scientifique
    75016 Paris (FR)
  • Université de Bordeaux
    33000 Bordeaux (FR)

(72) Inventors:
  • POTTIER, Agnès
    F-75006 Paris (FR)
  • LEVY, Laurent
    F-75014 Paris (FR)
  • MEYRE, Marie-Edith
    F-75012 Paris (FR)
  • GERMAIN, Matthieu
    F-94500 Champigny sur Marne (FR)
  • LORENZATO, Cyril
    F-47200 Marmande (FR)
  • MOONEN, Chrit
    F-33170 Gradignan (FR)
  • SMIRNOV, Pierre
    F-17000 La Rochelle (FR)

(74) Representative: Starck-Loudes, Anne-Caroline et al
Cabinet Becker & Associés 25, rue Louis le Grand
75002 Paris
75002 Paris (FR)


(56) References cited: : 
EP-A1- 2 067 485
WO-A2-2008/035985
US-A1- 2009 004 258
WO-A2-2008/033031
US-A1- 2007 197 904
   
  • AIME S ET AL: "Gd-loaded liposomes as T1, suseptibility, and CEST agents, all in one", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC; US, vol. 129, no. 9, 7 March 2007 (2007-03-07) , pages 2430-2431, XP002470078, ISSN: 0002-7863, DOI: DOI:10.1021/JA0677867
  • ARRUEBO ET AL: "Magnetic nanoparticles for drug delivery", NANO TODAY, ELSEVIER, AMSTERDAM, NL, vol. 2, no. 3, 4 May 2007 (2007-05-04), pages 22-32, XP022063172, ISSN: 1748-0132, DOI: DOI:10.1016/S1748-0132(07)70084-1
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).