(19)

(11)

EP 2 670 985 A1

(12)

(43) Date of publication: 11.12.2013 Bulletin 2013/50 (21) Application number: 11857830.1 (22) Date of filing: 31.01.2011

(51) International Patent Classification (IPC):  F15B 1/04(2006.01) (86) International application number: PCT/US2011/023120 (87) International publication number: WO 2012/105933 (09.08.2012 Gazette 2012/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (71) Applicant: Vanderbilt University Nashville, TN 37212 (US)	(72) Inventors: BARTH, Eric J. Nashville, Tennessee 37209 (US) PEDCHENKO, Alexander V. Nolensville, Tennessee 37135 (US) (74) Representative: Vaughan, Christopher Tammo  Harrison Goddard Foote LLP Belgrave Hall Belgrave Street Leeds LS2 8DD Leeds LS2 8DD (GB)