(19)

(11)

EP 2 675 903 A1

(12)

(43) Date of publication: 25.12.2013 Bulletin 2013/52 (21) Application number: 12719479.3 (22) Date of filing: 14.02.2012

(51) International Patent Classification (IPC):  C12N 15/861(2006.01) C12N 5/07(2010.01) C12N 5/10(2006.01) (86) International application number: PCT/US2012/025117 (87) International publication number: WO 2012/112603 (23.08.2012 Gazette 2012/34)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 14.02.2011 US 201161442695 P (71) Applicant: University of Utah Research Foundation Salt Lake City, UT 84108 (US)	(72) Inventors: PULST, Stefan, M. Salt Lake City, UT 84132 (US) PAUL, Sharan Salt Lake City, UT 84109 (US) DANSITHONG, Warunee Salt Lake City, UT 84109 (US) (74) Representative: Bösl, Raphael Konrad  Isenbruck Bösl Hörschler LLP Patentanwälte Prinzregentenstrasse 68 81675 München 81675 München (DE)