(19)
(11) EP 2 680 917 A1

(12)

(43) Date of publication:
08.01.2014 Bulletin 2014/02

(21) Application number: 11707985.5

(22) Date of filing: 04.03.2011
(51) International Patent Classification (IPC): 
A61M 31/00(2006.01)
A61F 2/82(2013.01)
(86) International application number:
PCT/US2011/027180
(87) International publication number:
WO 2012/121691 (13.09.2012 Gazette 2012/37)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(71) Applicant: Johns Hopkins University
Baltimore, MD 21218 (US)

(72) Inventors:
  • HWANG, Chao-Wei
    Ellicott City, MD 21043 (US)
  • TOMEY, Hala, J.
    Washington, DC 20008 (US)
  • RESAR, Jon, R.
    Stevenson, MD 21153 (US)
  • MATTESON, Robert, C., III
    Ellicott City, MD 21042 (US)
  • COLES, George, L., Jr.
    Baltimore, MD 21215 (US)
  • BENKOSKI, Jason, J.
    Ellicott City, MD 21043 (US)
  • TREXLER, Morgana, M.
    Baltimore, MD 21230 (US)

(74) Representative: Stork Bamberger 
Patentanwälte Postfach 73 04 66
22124 Hamburg
22124 Hamburg (DE)

   


(54) IMPLANTABLE PRESSURE-ACTUATED DRUG DELIVERY SYSTEMS AND METHODS OF MANUFACTURE AND USE