(19)
(11) EP 2 681 239 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
09.09.2015 Bulletin 2015/37

(45) Mention of the grant of the patent:
22.07.2015 Bulletin 2015/30

(21) Application number: 12706242.0

(22) Date of filing: 24.02.2012
(51) International Patent Classification (IPC): 
C07K 16/00(2006.01)
 C07K 16/22(2006.01)
(86) International application number:
PCT/EP2012/053118
(87) International publication number:
WO 2012/116926 (07.09.2012 Gazette 2012/36)

(54)

ANTIGEN BINDING PROTEINS

ANTIGENBINDENDE PROTEINE

PROTÉINES DE LIAISON À UN ANTIGÈNE

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 28.02.2011 EP 11156320

(43) Date of publication of application:
08.01.2014 Bulletin 2014/02

(73) Proprietor: F. Hoffmann-La Roche AG
4070 Basel (CH)

(72) Inventors:
  • BOSSENMAIER, Birgit
    82229 Seefeld (DE)
  • KETTENBERGER, Hubert
    81369 Muenchen (DE)
  • KLEIN, Christian
    CH-8906 Bonstetten (CH)
  • KUENKELE, Klaus-Peter
    85417 Marzling (DE)
  • REGULA, Joerg Thomas
    81377 Muenchen (DE)
  • SCHAEFER, Wolfgang
    68199 Mannheim (DE)
  • SCHWAIGER, Manfred
    85368 Wang-Bergen (DE)
  • SUSTMANN, Claudio
    81373 Muenchen (DE)

(74) Representative: Burger, Alexander et al
Roche Diagnostics GmbH Patent Department (LPP.....6164) P.O.Box 11 52
82372 Penzberg
82372 Penzberg (DE)


(56) References cited: : 
WO-A1-2006/093794
US-A1- 2010 322 934
 WO-A1-2010/145792
   
  • W. SCHAEFER ET AL: "Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 108, no. 27, 5 July 2011 (2011-07-05) , pages 11187-11192, XP055003817, ISSN: 0027-8424, DOI: 10.1073/pnas.1019002108
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).