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(11)

EP 2 686 308 A2

(12)

(88) Date of publication A3: 08.11.2012 (43) Date of publication: 22.01.2014 Bulletin 2014/04 (21) Application number: 12756938.2 (22) Date of filing: 15.03.2012

(51) International Patent Classification (IPC):  C07D 271/06(2006.01) C07D 401/04(2006.01) A61P 31/00(2006.01) C07D 213/72(2006.01) A61K 31/4245(2006.01) (86) International application number: PCT/US2012/029234 (87) International publication number: WO 2012/125832 (20.09.2012 Gazette 2012/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 15.03.2011 US 201161452884 P (71) Applicant: Rib-X Pharmaceuticals, Inc. New Haven, CT 06511 (US)	(72) Inventors: DUFFY, Erin, M. Deep River CT 06417 (US) CHEN, Shili Cheshire, CT 06410 (US) KANYO, Zoltan, F. North Haven, CT 06473 (US) GOLDBERG, Joel, A. New Orleans, LA 70118 (US) WANG, Deping Sharon, MA 02067 (US) TANG, Yuanqing Cheshire, CT 06410 (US) (74) Representative: Mintz Levin Cohn Ferris Glovsky and Popeo LLP  Alder Castle 10 Noble Street London EC2V 7JX London EC2V 7JX (GB)