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(11)

EP 2 688 402 A1

(12)

(43) Date of publication: 29.01.2014 Bulletin 2014/05 (21) Application number: 12761460.0 (22) Date of filing: 23.03.2012

(51) International Patent Classification (IPC):  A01N 43/04(2006.01) C08B 37/00(2006.01) A61K 31/715(2006.01) C07H 5/04(2006.01) (86) International application number: PCT/US2012/030233 (87) International publication number: WO 2012/129461 (27.09.2012 Gazette 2012/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 23.03.2011 US 201113069860 08.06.2011 WO PCT/US2011/039550 (71) Applicant: University of Utah Research Foundation Salt Lake City, UT 84108 (US)	(72) Inventors: PRESTWICH, Glenn, D. Eastsound WA 98245 (US) OOTTAMASATHIEN, Siam Salt Lake City UT 84106 (US) JIA, Wanjian Salt Lake City UT 84108 (US) MCCOARD, Lindsi Salt Lake City UT 84104 (US) LEE, Won, Yong Salt Lake City UT 84102 (US) (74) Representative: Campbell, Neil Boyd  Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)