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EP 2 688 901 A1

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(43) Date of publication: 29.01.2014 Bulletin 2014/05 (21) Application number: 12765822.7 (22) Date of filing: 26.03.2012

(51) International Patent Classification (IPC):  C07J 1/00(2006.01) A61K 31/566(2006.01) A61K 31/675(2006.01) A61K 51/04(2006.01) C12N 9/04(2006.01) A61K 31/565(2006.01) A61K 31/58(2006.01) A61K 31/69(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/CA2012/000316 (87) International publication number: WO 2012/129673 (04.10.2012 Gazette 2012/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 25.03.2011 US 201161467764 P (71) Applicant: Université Laval Quebec, QC G1V 0A6 (CA)	(72) Inventors: POIRIER, Donald L'Ancienne-Lorette Québec G2E 5V1 (CA) MALTAIS, René Québec Québec G2N 1T1 (CA) ROY, Jenny Saint-Jean-Chrysostome Québec G6Z 3R6 (CA) (74) Representative: Lahrtz, Fritz  Isenbruck Bösl Hörschler LLP Patentanwälte Prinzregentenstrasse 68 81675 München 81675 München (DE)