(19)
(11) EP 2 691 093 A1

(12)

(43) Date of publication:
05.02.2014 Bulletin 2014/06

(21) Application number: 12712866.8

(22) Date of filing: 30.03.2012
(51) International Patent Classification (IPC): 
A61K 31/381(2006.01)
A61K 31/4188(2006.01)
A61K 31/429(2006.01)
 A61K 31/407(2006.01)
A61K 31/424(2006.01)
A61K 31/12(2006.01)
(86) International application number:
PCT/US2012/031379
(87) International publication number:
WO 2012/135581 (04.10.2012 Gazette 2012/40)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 31.03.2011 US 201161470415 P

(71) Applicant: IDENIX Pharmaceuticals, Inc.
Cambridge, MA 02139 (US)

(72) Inventors:
  • DOUSSON, Cyril, B.
    F-34800 Canet (FR)
  • DUKHAN, David
    F-34980 Saint Gely Du Fesc (FR)
  • PARSY, Christopher, Claude
    F-34830 Jacou (FR)
  • PIERRA, Claire
    F-34570 Montarnaud (FR)
  • ALEXANDRE, Francois-Rene
    F-34090 Montpellier (FR)
  • BRANDT, Guillaume
    F-34000 Montpellier (FR)
  • DA COSTA, Daniel
    F-34430 Saint Jean De Vedas (FR)
  • RAHALI, Houcine
    F-30126 Saint Laurent Des Arbres (FR)
  • PAPARIN, Jean-Laurent
    F-34230 Vendemian (FR)
  • DEROCK, Michel
    F-34790 Grabels (FR)
  • CONVARD, Thierry
    F-69580 Sathonay-camp (FR)
  • SURLERAUX, Dominique
    B-1440 Wauthier-braine (BE)
  • BILELLO, John, P.
    Maynard, MA 01754 (US)

(74) Representative: Jones Day 
Rechtsanwälte, Attorneys-at-Law Patentanwälte Intellectual Property Prinzregentenstraße 11
80538 München
80538 München (DE)

   


(54) METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR