(19)
(11) EP 2 694 686 A2

(12)

(43) Date of publication:
12.02.2014 Bulletin 2014/07

(21) Application number: 12768638.4

(22) Date of filing: 06.04.2012
(51) International Patent Classification (IPC): 
C12Q 1/68(2006.01)
(86) International application number:
PCT/US2012/032489
(87) International publication number:
WO 2012/138973 (11.10.2012 Gazette 2012/41)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 06.04.2011 US 201161472435 P
27.07.2011 US 201161512334 P

(71) Applicant: The University of Chicago
Chicago, IL 60637 (US)

(72) Inventors:
  • HE, Chuan
    Chicago, IL 60637 (US)
  • ZHANG, Liang
    Chicago, IL 60637 (US)
  • SONG, Chunxiao
    Chicago, IL 60637 (US)
  • YU, Miao
    Chicago, IL 60637 (US)

(74) Representative: Roberts, Joanne Nicola 
J A Kemp 14 South Square Gray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-METHYLCYTOSINE (5mC)