Field of the Invention
[0001] The invention relates to a cleaning and isolation facility for pharmaceutical processing
equipment, in particular to a device for dust removal through air curtain isolation
and self-circulation purification, applied in a pharmaceutical clean area (i.e., pharmaceutical
clean room) to be able to guarantee sterile unidirectional flow inside the isolation
facility and also prevent dust and aerosol produced by the pharmaceutical processing
equipment during running from resulting in pollution and interference to the environment
of both the processing area and the whole clean area.
Description of the Prior Art
[0002] For pharmaceutical enterprises, dust produced by equipment, for example a capping
machine running in the clean area, will result in pollution and interference to 'the
environment of both the processing area and the whole clean area. The capping machine
is equipment for sealing drug containers, which have been filled and stoppered or
have been freeze-dried and corked, by an aluminum cap and aluminum plastics. After
a drug container has been filled and stoppered but before capped and sealed, the connection
between the rubber stopper and the bottleneck is in an Incomplete Seal status, there
is a possibility of loosing even bouncing of the stopper. The capping machine in a
capping workshop during capping will produce a lot of suspended aluminum scraps, glass
chips, aerosol and other kinds of dust, which are difficult to detect. Such dust produced
by the capping machine constitutes a serious pollution threat to the sterile status
of the capping workshop area. Meanwhile, such dust will spread around through the
purification and air-conditioning system of the whole clean area, thereby resulting
in extensive pollution to the environment of the whole clean area for pharmaceutical
manufacturing and interference to the purification and air-conditioning system of
the clean area.
[0003] The Minimum Requirement on capping of non-terminally sterilized products in Chinese
GMP (Good Manufacturing Practice) Version 1998 is Grade 100,000 (Grade D). The GMP
Version 2010 revised by the State Food and Drug Administration specifies that capping
of non-terminally sterilized products must be done in a Grade A environment under
Grade B background. However, in the prior art, the requirements in the new version
of GMP cannot be met due to the pollution of aluminum scraps, glass chips and aerosol
to the capping workshop. Generally, most pharmaceutical enterprises place the capping
machine in a Grade 100 laminar hood in a Grade 100,000 capping workshop for running,
as a result, the cleanness of the capping area is difficult to meet the standard requirements.
Dust, particles and aerosol may also be produced during other procedures of pharmaceutical
manufacturing, for example, during the processing and sub-packaging of bacterial and
virus species, contraceptives, antineoplastic drugs, radiochemicals and highly toxic
products, in addition to the foregoing capping and sealing procedures of pharmaceutical
manufacturing, thereby resulting in pollution and interference to operators and the
environment of the whole clean area. Therefore, the prior art has problems and deficiencies
that the cleanness of the environment of the pharmaceutical processing area is difficult
to meet the standard requirements.
Summary of the Invention
[0004] It is an object of the present invention to provide a device for dust removal through
air curtain isolation and self-circulation purification, in order to isolate dust
produced by the processing equipment in the area where it is produced and remove the
dust at the moment when it is produced by means of air curtain isolation and self-circulation
purification, thereby avoiding the spreading of dust resulting in pollution and interference
to the environment of both the processing area and the whole clean area and facilitating
the cleanness of the pharmaceutical processing environment to meet the standard requirements
in the Chinese GMP Version 2010.
[0005] For achieving the above stated object, a device, for dust removal through air curtain
isolation and self-circulation purification, comprises a material input transferring
cabin;
[0006] a main isolation cabin, having a front wall, a back wall, a left wall, and a right
wall, for placing and isolating a processing equipment which is placed inside the
main isolation cabin, each wall has a top and a bottom, the main isolation cabin being
connected to the material input transferring cabin through a material inlet that is
formed on a wall between the main input transferring cabin and the main isolation
cabin; a material output transferring cabin connected to the main isolation cabin
through a material outlet that is formed on a wall between the main isolation cabin
and the material output transferring cabin; and
[0007] a control cabinet containing an automatic control device for adjusting, displaying,
and recording air volume, pressure differential, and a number of suspended particles
in the main isolation cabin, the material input transferring cabin, and the material
output transferring cabin;
[0008] characterized in that, the main isolation cabin is a sealed cabin surrounded by walls,
the material input transferring cabin and the material output transferring cabin are
respectively disposed on left side and right side of the main isolation cabin, a material
input hole is formed on a left wall of the material input transferring cabin, a material
output hole is formed on a right wall of the material output transferring cabin; a
first laminar flow filtering hood, a second laminar flow filtering hood and a third
laminar flow filtering hood connect to and seal respectively a top of the main isolation
cabin, a top of the material input transferring cabin, and a top of the material output
transferring cabin, the first laminar flow filtering hood has an air supply surface,
a first air inlet is formed on a sidewall of the second laminar flow filtering hood
and a second air inlet is formed on a sidewall of the third laminar flow filtering
hood, a first air passage is formed between a bottom of the material input transferring
cabin and the ground, a second air passage is formed between a bottom of the material
output transferring cabin and the ground;
[0009] a self-circulation air pipe with a lower end and an upper end is vertically attached
to the front wall of the main isolation cabin, a waste container with an open top
and a lower interface is placed inside the main isolation cabin below the processing
equipment, the lower interface of the waste container enables the main isolation cabin
to communicate with the lower end of the self-circulation air pipe;
[0010] a plurality of filters and a fan are placed inside the self circulation air pipe,
the upper end of the self-circulation air pipe connects to the first laminar flow
filtering hood, and the lower end of the self-circulation air pipe connects to the
lower interface of the waste container;
[0011] an inlet reduction spreader plate with a top portion and a lower portion and an outlet
reduction spreader plate with a top portion are installed inside the main isolation
cabin in parallel with left and right walls of the main isolation cabin respectively,
a first gap interlayer is placed between the inlet reduction spreader plate and the
left wall of the main isolation cabin forming an inlet spreader air curtain passage,
a second gap interlayer is placed between the outlet reduction spreader plate and
the right wall of the main isolation cabin forming an outlet spreader air curtain
passage, the top portions of the inlet reduction spreader plate and the outlet reduction
spreader plate are close to the air supply surface of the laminar flow filtering hood,
the lower portions of the inlet reduction spreader plate and the outlet reduction
spreader plate are respectively provided with a reduction plate inlet and a reduction
plate outlet at positions corresponding to the material inlet and the material outlet.
[0012] Preferably, each wall of the main isolation cabin has a bottom and a plastic plate
sealing off the bottom of the four walls to isolate the main isolation cabin from
the ground, and, the air passages are formed between the lower portions of the walls
of the material input transferring cabin and the material output transferring cabin,
excepting the wall adjacent to the main isolation cabin, and the ground.
[0013] Preferably, the filters in the self-circulation air pipe comprise a plug-board coarse-efficiency
filter and a plug-board medium-efficiency filter.
[0014] Preferably, the waste container has a funnel shape and a lower portion for collecting
dust of large particles.
[0015] Preferably, a sealed door and a glove box are disposed on the back wall of the main
isolation cabin.
[0016] Preferably, the top of each of the front wall, back wall, left wall, and right wall
of the main isolation cabin are sealingly attached to the first laminar flow filtering
hood, and only the bottom of the front wall and back wall of the main isolation cabin
are sealingly attached to a workbench.
[0017] Preferably, edges of the inlet reduction spreader plate and the outlet reduction
spreader plate are respectively sealingly attached to the front wall and back wall
of the main isolation cabin.
[0018] Preferably, all the walls are made from transparent glass or transparent organic
glass sheets, and the edge of each wall comprises a metal frame.
[0019] For achieving the above stated object, another device, for dust removal through air
curtain isolation and self-circulation purification, comprising a material input transferring
cabin with a bottom, a main isolation cabin, with a center, a front wall, a back wall,
a left wall, and a right wall, each wall has a top and a bottom, attached to the material
input transferring cabin and containing an processing equipment, a material output
transferring cabin, with a bottom, attached to the main isolation cabin, and a control
cabinet attached to the material output transferring cabin;
[0020] characterized in that the main isolation cabin is a sealed cabin surrounded by walls,
the material input transferring cabin is disposed on the left side of the main isolation
cabin, a material input hole is formed on a left wall of the material input transferring
cabin, a material inlet is formed on a wall between the main isolation cabin and the
material input transferring cabin and enables communication between the main isolation
cabin and the material input transferring cabin;
[0021] the material output transferring cabin is disposed on right side of the main isolation
cabin, a material output hole is formed on a right wall of the material output transferring
cabin, and a material outlet is formed on a wall between the main isolation cabin
and the material output transferring cabin and enables communication between the main
isolation cabin and the material output transferring cabin;
[0022] the control cabinet is an automatic control device for adjusting, displaying, and
recording air volume, pressure difference and a number of suspended particles in the
main isolation cabin, the material input transferring cabin, and the material output
transferring cabin;
[0023] all the walls are made from transparent glass or transparent organic glass sheets,
and the edge of each wall comprises a metal frame;
[0024] a first laminar flow filtering hood, a second high-efficiency laminar flow filtering
hood and a third high-efficiency laminar flow filtering hood are respectively sealingly
attached to top of the main isolation cabin, the material input transferring cabin
and the material output transferring cabin, an air inlet is formed on each of the
second filtering laminar high-efficiency flow hood and the third high-efficiency laminar
flow filtering hood, and a first air passage is formed between the bottom of the material
input transferring cabin and the ground, a second air passage is formed between the
bottom of the material output transferring cabin and the ground; the main isolation
cabin has four walls, each wall has a bottom, and a plastic plate sealing off the
bottoms of the four walls to isolate the main isolation cabin from the ground, and,
the air passages are formed between the lower portions of the walls of the material
input transferring cabin and the material output transferring cabin, excepting the
wall adjacent to the main isolation cabin, and the ground;
[0025] the processing equipment is disposed in the center of the main isolation cabin, a
self-circulation air pipe, with a middle, a lower end, and an upper end, is vertically
attached to the front wall of the main isolation cabin, a waste container with a top
opening is disposed inside the main isolation cabin and below the processing equipment,
the waste container, having a caisson shape lower portion for collecting dust of large
particles, is provided with a lower interface facing the front wall of the main isolation
cabin and allowing communication with a lower end of the self-circulation air pipe;
[0026] the self-circulation air pipe is provided with a plurality of filters and a fan placed
respectively at the middle and the upper end of the self-circulation air pipe, the
self-circulation air pipe communicates with the first high-efficiency laminar flow
filtering hood, and the lower end of the self-circulation air pipe is in communication
with the lower interface of the waste container, a sealed door and a glove box are
disposed on the back wall of the main isolation cabin;
[0027] the top of each wall of the main isolation cabin is sealing attached to the first
high-efficiency laminar flow filtering hood, and the bottoms of the front wall and
back wall of the main isolation cabin are stealing attached to a workbench, the top
of each of the walls adjacent to the main isolation cabin, the material input transferring
cabin and the material output transferring cabin is sealing attached to the first
high-efficiency laminar flow filtering hood, but the bottoms of the walls are not
sealing attached to a workbench and without providing with the material inlet and
the material outlet;
[0028] an inlet reduction spreader plate and an outlet reduction spreader plate are disposed
inside the main isolation cabin in parallel, respectively, with the left wall and
the right wall of the main isolation cabin, a first gap interlayer is formed between
the inlet reduction spreader plate and the left wall of the main isolation cabin and
a second gap interlayer is formed between the outlet reduction spreader plate and
the right wall of the main isolation cabin, the first gap interlayer and the second
gap interlayer form an inlet spreader air curtain passage and an outlet spreader air
curtain passage, edges of the inlet reduction spreader plate and the outlet reduction
spreader plate are respectively sealing attached to the front wall and back wall of
the main isolation cabin, top portions of the inlet reduction spreader plate and the
outlet reduction spreader plate are adjacent to an air supply surface on the high-efficiency
laminar flow filtering hood, and lower portions of the inlet reduction spreader plate
and the outlet reduction spreader plate are respectively provided with a reduction
plate inlet and a reduction plate outlet at positions corresponding to the material
inlet and the material outlet;
[0029] The working process of the present invention is as follows:
[0030] During processing, the processing equipment is placed inside the main isolation cabin;
and the material is fed into the main isolation cabin through the material input hole,
the material input transferring cabin, the material input hole, the inlet spreader
air curtain passage and the reduction plate inlet, processed by the processing equipment,
and then output from the reduction plate outlet, the outlet spreader air curtain passage
and the material outlet through the material output transferring cabin and the material
output hole.
[0031] Air flows in each isolation cabin as below: air in the top portion of the clean room
is directly extracted by the second laminar flow filtering hood in the material input
transferring cabin and the third laminar flow filtering hood in the material output
transferring cabin, and then filtered by the respective high-efficiency filters thereof
to form a vertically downwards laminar flow which is called the isolation air curtain
inside the material input transferring cabin and the material output transferring
cabin; and then, the airflow of the isolation air curtain returns back to the clean
room from the air passage between the bottom of the material input transferring cabin
and the material output transferring cabin, and the ground.
[0032] Dust-contained air inside the main isolation cabin is pumped into the self-circulation
air pipe by the fan in the first laminar flow filtering hood, and then filtered by
the coarse-efficiency, medium-efficiency and high-efficiency filters to form a vertical
laminar flow below the first laminar flow filtering hood, most air enters into the
working area of the processing equipment inside the main isolation cabin, a small
amount of air forms a vertically downwards laminar flow in the inlet spreader air
curtain passage and the outlet spreader air curtain passage due to the spreading of
the inlet reduction spreader plate and the outlet reduction spreader plate to form
a spreader air curtain, and, the clean air from the spreader air curtain flows downward
and is pumped into the main isolation cabin from the reduction plate inlet and a reduction
plate outlet, to compensate the spreading loss of the total air supply amount from
the first laminar flow filtering hood on the top of the main isolation cabin.
[0033] There may be slight dispersion or mix between the spreader air curtain at the reduction
plate inlet and the isolation air curtain inside the material input transferring cabin
and also slight dispersion or mix between the spreader air curtain at the reduction
plate outlet and the isolation air curtain inside the material output transferring
cabin, due to the relatively negative pressure formed between the main isolation cabin
and the reduction plate inlet and reduction plate outlet, the clean air from the isolation
air curtain is forced to enter into the main isolation cabin in one direction, thereby
guaranteeing a sterile environment inside the main isolation cabin and also isolating
and preventing dust produced by the processing equipment in the main isolation cabin
from spreading to the clean room; both the dust-contained air at the lower portion
of the main isolation cabin and the air supplemented through the reduction plate inlet
and reduction plate outlet are pumped into the self-circulation air pipe, then filtered
off coarse dust by the plug-board coarse-efficiency filter and the plug-board medium-efficiency
filter, and finally filtered by the first laminar flow filtering hood to circularly
flow inside the main isolation cabin and the self-circulation air pipe; characterized
in that, large particle of dust is collected in the bottom of the waste container,
and small particle of dust is filtered off by the plug-board coarse-efficiency filter
and the plug-board medium-efficiency filter; in this way, dust produced by the processing
equipment is isolated in the area where it is produced and removed at the moment when
it is produced.
[0034] The glove box and the sealed door are arranged such that, when the processing equipment
needs manual intervention, the operator may perform intervention to the processing
equipment in the main isolation cabin through rubber gloves in the glove box; and
at the end of processing, the operator may open the sealed door to clean, sterilize
and maintain the main isolation cabin and the equipment therein.
[0035] Compared with the prior art, in the present invention,
[0036] for procedures such as capping of non-terminally sterilized products, Annex 1 Sterile
Medical Products in the officially issued Chinese GMP Version 2010 (effective on Mar.
3, 2011) is known as "the sterile manufacturing procedures of the following non-terminally
sterilized products must be done in Grade A under Grade B background: operating and
transporting (filling or encapsulating, sub-packaging, corking, capping, etc.) of
products in an Incomplete Seal status, as well as crushing, sieving and etc. of sterile
raw materials", and later supplemented by two points: "(1) products are regarded to
be in an Incomplete Seal status before capped, (2) due to factors such as the tightness
of the corked products, the design of the capping equipment and the property of the
aluminum cap, capping may be done in a Grade A air supply environment under Grade
C or D background, and the Grade A air supply environment should at least be in accordance
with the static requirement of the Grade A area". On this basis, in a case that the
device provided by the invention is applied under Grade C or D background, medium-efficiency
filters have to be additionally provided at indoor air inlets of the second laminar
flow filtering hood and the third laminar flow filtering hood, then the quality of
the Grade A vertical laminar flow air and the service life of the high-efficiency
filters in each isolation cabin may be guaranteed.
[0037] In addition, the number of the material input transferring cabins and the material
output transferring cabins in the invention may be increased or decrease; or even,
the material input transferring cabins and the material output transferring cabins
may be integrated, depending on the process requirement.
[0038] In conclusion, by employing a technical solution where three independent interlayer
isolation cabins including a main isolation cabin, a material input transferring cabin
and a material output transferring cabin are provided, a self-circulation purification
device formed of self-circulation air pipes with a plug-board coarse-efficiency filter
and a plug-board medium-efficiency filter is disposed in the main isolation cabin,
and an airflow cleaning air curtain formed of an inlet airflow air curtain passage
and an outlet airflow air curtain passage is respectively disposed between the main
isolation cabin and the material input transferring cabin and also between the main
isolation cabin and the material output transferring cabin, the invention overcomes
the problems and deficiencies in the prior art that the cleanness of the environment
of the pharmaceutical processing area is difficult to meet the standard requirements.
The device for dust removal through air curtain isolation and self-circulation purification
provided by the invention isolates dust produced by the processing equipment in the
area where it is produced and removes it at the moment when it is produced by means
of air curtain isolation and self-circulation purification, thereby avoiding the spreading
of dust resulting in pollution and interference to the environment of both the processing
area and the whole clean area and facilitating the cleanness of the pharmaceutical
processing environment to meet the standard requirements in the Chinese GMP Version
2010.
Brief Description of the Drawings
[0039]
Fig. 1 is a structure diagram of a device in accordance with the embodiment of the
present invention;
Fig. 2 is a top plan view of Fig. 1;
Fig. 3 is a sectional view of Fig. 2 in direction A-A.
Detailed description of the preferred embodiment
[0040] To enable a further understanding of the innovative and technological content of
the invention herein, refer to the detailed description of the invention and the accompanying
drawings below:
[0041] As shown in Fig. 1 to Fig. 3, as a preferred embodiment of the invention, the device
for dust removal through air curtain isolation and self-circulation purification comprises
a material input transferring cabin 1, a main isolation cabin 2 for placing and isolating
a processing equipment 6, a material output transferring cabin 3 and a control cabinet
7.
[0042] The main isolation cabin 2 is a sealed cabin surrounded by walls, the material input
transferring cabin 1 and the material output transferring cabin 3 are respectively
disposed on left side and right side of the main isolation cabin 2, the main isolation
cabin 2 is connected to the material input transferring cabin 1 through a material
inlet 11 that is formed on a wall between the main input transferring cabin 1 and
the main isolation cabin 2, and the main isolation cabin 2 is connected to the material
output transferring cabin 3 through a material outlet 31 that is formed on a wall
between the main isolation cabin and the material output transferring cabin.
[0043] The material input transferring cabin 1 is connected to other external facilities
through a material input hole 111 formed on a left wall of the material input transferring
cabin 1, and the material output transferring cabin 3 is connected to outside through
a material output hole 311 formed on a right wall of the material output transferring
cabin 3.
[0044] The control cabinet 7 contains an automatic control device for adjusting, displaying,
and recording air volume, pressure differential, and a number of suspended particles
in the main isolation cabin 2, the material input transferring cabin 1 and the material
output transferring cabin 3.
[0045] All the walls are made from transparent glass or transparent organic glass sheets,
and the edge of each wall comprises a metal frame.
[0046] A first laminar flow filtering hood 5, a second laminar flow filtering hood 51 and
a third laminar flow filtering hood 52 connect to and seal respectively a top of the
main isolation cabin 2, a top of the material input transferring cabin 1 and a top
of the material output transferring cabin 3, the first laminar flow filtering hood
has an air supply surface, a first air inlet is formed on a sidewall of the second
laminar flow filtering hood 51, and a second air inlet is formed on a sidewall of
the third laminar flow filtering hood 52; and each wall of the main isolation cabin
2 has a bottom and a plastic plate sealing off the bottom of the four walls to isolate
the main isolation cabin 2 from the ground, and, the air passages are formed between
the lower portions of the walls of the material input transferring cabin 1 and the
material output transferring cabin 3, excepting the wall adjacent to the main isolation
cabin 2, and the ground.
[0047] The processing equipment 6 is placed inside the main isolation cabin 2, a waste container
23 with an open top and a lower interface is placed inside the main isolation cabin
2 below the processing equipment 6, the waste container 23 has a funnel shape and
a lower portion for collecting dust of large particles, the lower interface 23a of
the waste container enables the main isolation cabin 2 to communicate with the lower
end of the self-circulation air pipe 21, and the lower interface 23a of the waste
container 23 is enabled to pass through the front wall of the main isolation cabin
2 to communicate with the lower end of the self-circulation air pipe 21.
[0048] A plurality of filters and a fan are placed inside the self circulation air pipe
21, the filters in the self-circulation air pipe 21 comprise a plug-board coarse-efficiency
filter 24 and a plug-board medium-efficiency filter 25, the upper end of the self-circulation
air pipe 21 connects to the first laminar flow filtering hood 5, and the lower end
of the self-circulation air pipe 21 connects to the lower interface 23a of the waste
container 23; and a sealed door 42 and a glove box 41 are disposed on the back wall
of the main isolation cabin 2.
[0049] The top of each of the front wall and back wall of the main isolation cabin 2 is
sealingly attached to the first laminar flow filtering hood 5, and only the bottom
of the front wall and back wall of the main isolation cabin 2 are sealingly attached
to a workbench; the top of each of the walls of the main isolation cabin 2 adjacent
to the material input transferring cabin 1 and the material output transferring cabin
3 is sealingly attached to the first laminar flow filtering hood 5, the bottom of
the walls of the main isolation cabin 2 are not sealingly attached to a workbench,
and the material inlet 11 and the material outlet 31 are respectively formed on the
walls.
[0050] An inlet reduction spreader plate 12 with a top portion and a lower portion and an
outlet reduction spreader plate 32 with a top portion are installed inside the main
isolation cabin 2 in parallel with left and right walls of the main isolation cabin
2 respectively, a first gap interlayer is placed between the inlet reduction spreader
plate 12 and the left wall of the main isolation cabin 2 forming an inlet spreader
air curtain passage, and a second gap interlayer is placed between the outlet reduction
spreader plate 32 and the right wall of the main isolation cabin 2 forming an outlet
spreader air curtain passage; the vertical edge of the inlet reduction spreader plate
12 and the outlet reduction spreader plate 32 is sealingly connected to the front
wall and back wall of the main isolation cabin 2, respectively; the top portions of
the inlet reduction spreader plate 12 and the outlet reduction spreader plate 32 are
close to the air supply surface of the laminar flow filtering hood 5, and the lower
portions of the inlet reduction spreader plate 12 and the outlet reduction spreader
plate 32 are respectively provided with a reduction plate inlet 112 and a reduction
plate outlet 312 at positions corresponding to the material inlet 11 and the material
outlet 31.
[0051] The working process of the present invention is as follows:
[0052] During processing, the processing equipment 6 is placed inside the main isolation
cabin 2; and the material is fed into the main isolation cabin 2 through the material
input hole 111, the material input transferring cabin 1, the material input hole 11,
the inlet spreader air curtain passage 26 and the reduction plate inlet 112, processed
by the processing equipment 6, and then output from the reduction plate outlet 312,
the outlet spreader air curtain passage 27 and the material outlet 31 through the
material output transferring cabin 3 and the material output hole 311.
[0053] Air flows in each isolation cabin as below: air in the top portion of the clean room
is directly extracted by the second laminar flow filtering hood 51 in the material
input transferring cabin 1 and the third laminar flow filtering hood 52 in the material
output transferring cabin 3, and then filtered by the respective high-efficiency filters
thereof to form a vertically downwards laminar flow which is called the isolation
air curtain inside the material input transferring cabin 1 and the material output
transferring cabin 3; and then, the airflow of the isolation air curtain returns back
to the clean room from the air passage between the bottom of the material input transferring
cabin 1 and the material output transferring cabin 3, and the ground.
[0054] Dust-contained air inside the main isolation cabin 2 is pumped into the self-circulation
air pipe 21 by the fan in the first laminar flow filtering hood 5, and then filtered
by the coarse-efficiency, medium-efficiency and high-efficiency filters to form a
vertical laminar flow below the first laminar flow filtering hood 5, most air enters
into the working area of the processing equipment 6 inside the main isolation cabin
2, a small amount of air forms a vertically downwards laminar flow in the inlet spreader
air curtain passage 26 and the outlet spreader air curtain passage 27 due to the spreading
of the inlet reduction spreader plate 12 and the outlet reduction spreader plate 32
to form a spreader air curtain, and, the clean air from the spreader air curtain flows
downward and is pumped into the main isolation cabin from the reduction plate inlet
112 and a reduction plate outlet 312, to compensate the spreading loss of the total
air supply amount from the first laminar flow filtering hood 5 on the top of the main
isolation cabin 2.
[0055] There may be slight dispersion or mix between the spreader air curtain at the reduction
plate inlet 112 and the isolation air curtain inside the material input transferring
cabin 1 and also slight dispersion or mix between the spreader air curtain at the
reduction plate outlet 312 and the isolation air curtain inside the material output
transferring cabin 3, due to the relatively negative pressure formed between the main
isolation cabin 2 and the reduction plate inlet 112 and reduction plate outlet 312,
the clean air from the isolation air curtain is forced to enter into the main isolation
cabin 2 in one direction, thereby guaranteeing a sterile environment inside the main
isolation cabin 2 and also isolating and preventing dust produced by the processing
equipment 6 in the main isolation cabin 2 from spreading to the clean room; both the
dust-contained air at the lower portion of the main isolation cabin 2 and the air
supplemented through the reduction plate inlet 112 and reduction plate outlet 312
are pumped into the self-circulation air pipe 21, then filtered off coarse dust by
the plug-board coarse-efficiency filter 24 and the plug-board medium-efficiency filter
25, and finally filtered by the first laminar flow filtering hood 5 to circularly
flow inside the main isolation cabin 2 and the self-circulation air pipe 21; wherein,
large particle of dust is collected in the bottom of the waste container 23, and small
particle of dust is filtered off by the plug-board coarse-efficiency filter 24 and
the plug-board medium-efficiency filter 25; in this way, dust produced by the processing
equipment 6 is isolated in the area where it is produced and removed at the moment
when it is produced.
[0056] The glove box 41 and the sealed door 42 are arranged such that, when the processing
equipment 6 needs manual intervention, the operator may perform intervention to the
processing equipment 6 in the main isolation cabin 2 through rubber gloves in the
glove box 41; and at the end of processing, the operator may open the sealed door
42 to clean, sterilize and maintain the main isolation cabin 2 and the equipment therein.
1. A device, for dust removal through air curtain isolation and self-circulation purification,
comprising:
a material input transferring cabin (1);
a main isolation cabin (2), having a front wall, a back wall, a left wall, and a right
wall, for placing and isolating a processing equipment (6) which is placed inside
the main isolation cabin (2), each wall has a top and a bottom, the main isolation
cabin (2) being connected to the material input transferring cabin (1) through a material
inlet (11) that is formed on a wall between the main input transferring cabin (1)
and the main isolation cabin (2);
a material output transferring cabin (3) connected to the main isolation cabin (2)
through a material outlet (31) that is formed on a wall between the main isolation
cabin and the material output transferring cabin; and
a control cabinet (7) containing an automatic control device for adjusting, displaying,
and recording air volume, pressure differential, and a number of suspended particles
in the main isolation cabin, the material input transferring cabin, and the material
output transferring cabin;
characterized in that,
the main isolation cabin (2) is a sealed cabin surrounded by walls, the material input
transferring cabin (1) and the material output transferring cabin (3) are respectively
disposed on left side and right side of the main isolation cabin (2), a material input
hole (111) is formed on a left wall of the material input transferring cabin (1),
a material output hole (311) is formed on a right wall of the material output transferring
cabin (3);
a first laminar flow filtering hood (5), a second laminar flow filtering hood (51)
and a third laminar flow filtering hood (52) connect to and seal respectively a top
of the main isolation cabin (2), a top of the material input transferring cabin (1),
and a top of the material output transferring cabin (3), the first laminar flow filtering
hood has an air supply surface,
a first air inlet is formed on a sidewall of the second laminar flow filtering hood
(51) and a second air inlet is formed on a sidewall of the third laminar flow filtering
hood (52), a first air passage is formed between a bottom of the material input transferring
cabin (1) and the ground, a second air passage is formed between a bottom of the material
output transferring cabin (3) and the ground;
a self-circulation air pipe (21) with a lower end and an upper end is vertically attached
to the front wall of the main isolation cabin (2), a waste container (23) with an
open top and a lower interface is placed inside the main isolation cabin (2) below
the processing equipment (6), the lower interface (23a) of the waste container enables
the main isolation cabin (2) to communicate with the lower end of the self-circulation
air pipe (21);
a plurality of filters and a fan are placed inside the self circulation air pipe,
the upper end of the self-circulation air pipe (21) connects to the first laminar
flow filtering hood (5), and the lower end of the self-circulation air pipe (21) connects
to the lower interface (23a) of the waste container (23);
an inlet reduction spreader plate (12) with a top portion and a lower portion and
an outlet reduction spreader plate (32) with a top portion are installed inside the
main isolation cabin (2) in parallel with left and right walls of the main isolation
cabin (2) respectively, a first gap interlayer is placed between the inlet reduction
spreader plate (12) and the left wall of the main isolation cabin (2) forming an inlet
spreader air curtain passage, a second gap interlayer is placed between the outlet
reduction spreader plate (32) and the right wall of the main isolation cabin (2) forming
an outlet spreader air curtain passage, the top portions of the inlet reduction spreader
plate (12) and the outlet reduction spreader plate (32) are close to the air supply
surface of the laminar flow filtering hood (5), the lower portions of the inlet reduction
spreader plate (12) and the outlet reduction spreader plate (32) are respectively
provided with a reduction plate inlet (112) and a reduction plate outlet (312) at
positions corresponding to the material inlet (11) and the material outlet (31).
2. The device for dust removal according to claim 1, characterized in that each wall of the main isolation cabin (2) has a bottom and a plastic plate sealing
off the bottom of the four walls to isolate the main isolation cabin (2) from the
ground, and, the air passages are formed between the lower portions of the walls of
the material input transferring cabin (1) and the material output transferring cabin
(3), excepting the wall adjacent to the main isolation cabin (2), and the ground.
3. The device for dust removal according to claim 1, characterized in that the filters in the self-circulation air pipe (21) comprise a plug-board coarse-efficiency
filter (24) and a plug-board medium-efficiency filter (25).
4. The device for dust removal according to claim 1, characterized in that the waste container (23) has a funnel shape and a lower portion for collecting dust
of large particles.
5. The device for dust removal according to claim 1, characterized in that a sealed door (42) and a glove box (41) are disposed on the back wall of the main
isolation cabin (2).
6. The device for dust removal according to claim 1, characterized in that the top of each of the front wall, back wall, left wall, and right wall of the main
isolation cabin (2) are sealingly attached to the first laminar flow filtering hood
(5), and only the bottom of the front wall and back wall of the main isolation cabin
(2) are sealingly attached to a workbench.
7. The device for dust removal according to claim 1, characterized in that edges of the inlet reduction spreader plate (12) and the outlet reduction spreader
plate (32) are respectively sealingly attached to the front wall and back wall of
the main isolation cabin (2).
8. The device for dust removal according to claim 1, characterized in that all the walls are made from transparent glass or transparent organic glass sheets,
and the edge of each wall comprises a metal frame.
9. A device, for dust removal through air curtain isolation and self-circulation purification,
comprising a material input transferring cabin (1) with a bottom, a main isolation
cabin (2), with a center, a front wall, a back wall, a left wall, and a right wall,
each wall has a top and a bottom, attached to the material input transferring cabin
and containing an processing equipment (6), a material output transferring cabin (3),
with a bottom, attached to the main isolation cabin, and a control cabinet (7) attached
to the material output transferring cabin (3);
characterized in that the main isolation cabin (2) is a sealed cabin surrounded by walls, the material
input transferring cabin (1) and the material output transferring cabin (3) are respectively
disposed on left side and right side of the main isolation cabin (2), a material input
hole (111) is formed on a left wall of the material input transferring cabin (1),
a material output hole (311) is formed on a right wall of the material output transferring
cabin (3), a material inlet (11) is formed on a wall between the main isolation cabin
(2) and the material input transferring cabin (1) and enables communication between
the main isolation cabin (2) and the material input transferring cabin (1), and a
material outlet (31) is formed on a wall between the main isolation cabin (2) and
the material output transferring cabin (3) and enables communication between the main
isolation cabin (2) and the material output transferring cabin (3);
the control cabinet (7) is an automatic control device for adjusting, displaying,
and recording air volume, pressure difference and a number of suspended particles
in the main isolation cabin (2), the material input transferring cabin (1), and the
material output transferring cabin (3);
a first laminar flow filtering hood (5), a second high-efficiency laminar flow filtering
hood (51) and a third high-efficiency laminar flow filtering hood (52) are respectively
sealingly attached to top of the main isolation cabin (2), the material input transferring
cabin (1) and the material output transferring cabin (3), an air inlet is formed on
each of the second filtering laminar high-efficiency flow hood (51) and the third
high-efficiency laminar flow filtering hood (52), and a first air passage is formed
between the bottom of the material input transferring cabin (1) and the ground, a
second air passage is formed between the bottom of the material output transferring
cabin (3) and the ground;
the processing equipment (6) is disposed in the center of the main isolation cabin
(2), a self-circulation air pipe (21), with a middle, a lower end, and an upper end,
is vertically attached to the front wall of the main isolation cabin (2), a waste
container (23) with a top opening is disposed inside the main isolation cabin (2)
and below the processing equipment (6), the waste container (23) is provided with
a lower interface (23a) facing the front wall of the main isolation cabin (2) and
allowing communication with a lower end of the self-circulation air pipe (21);
the self-circulation air pipe (21) is provided with a plurality of filters and a fan
placed respectively at the middle and the upper end of the self-circulation air pipe
(21), the self-circulation air pipe communicates with the first high-efficiency laminar
flow filtering hood (5), and the lower end of the self-circulation air pipe (21) is
in communication with the lower interface (23a) of the waste container (23);
an inlet reduction spreader plate (12) and an outlet reduction spreader plate (32)
are disposed inside the main isolation cabin (2) in parallel, respectively, with the
left wall and the right wall of the main isolation cabin (2), a first gap interlayer
is formed between the inlet reduction spreader plate (12) and the left wall of the
main isolation cabin (2) and a second gap interlayer is formed between the outlet
reduction spreader plate (32) and the right wall of the main isolation cabin (2),
the first gap interlayer and the second gap interlayer form an inlet spreader air
curtain passage (26) and an outlet spreader air curtain passage (27), top portions
of the inlet reduction spreader plate (12) and the outlet reduction spreader plate
(32) are adjacent to an air supply surface on the high-efficiency laminar flow filtering
hood (5), and lower portions of the inlet reduction spreader plate (12) and the outlet
reduction spreader plate (32) are respectively provided with a reduction plate inlet
(112) and a reduction plate outlet (312) at positions corresponding to the material
inlet (11) and the material outlet (31);
the main isolation cabin (2) has four walls, each wall has a bottom, and a plastic
plate sealing off the bottoms of the four walls to isolate the main isolation cabin
(2) from the ground, and, the air passages are formed between the lower portions of
the walls of the material input transferring cabin (1) and the material output transferring
cabin (3), excepting the wall adjacent to the main isolation cabin (2), and the ground;
the filters in the self-circulation air pipe (21) comprise a plug-board coarse-efficiency
filter (24) and a plug-board medium-efficiency filter (25);
the waste container (23) has a funnel shape and a caisson shape lower portion for
collecting dust of large particles;
a sealed door (42) and a glove box (41) are disposed on the back wall of the main
isolation cabin (2);
the top of each wall of the main isolation cabin (2) is sealing attached to the first
high-efficiency laminar flow filtering hood (5), and the bottoms of the front wall
and back wall of the main isolation cabin (2) are sealing attached to a workbench;
edges of the inlet reduction spreader plate (12) and the outlet reduction spreader
plate (32) are respectively sealing attached to the front wall and back wall of the
main isolation cabin (2);
all the walls are made from transparent glass or transparent organic glass sheets,
and the edge of each wall comprises a metal frame.