(19)

(11)

EP 2 712 320 A1

(12)

(43) Date of publication: 02.04.2014 Bulletin 2014/14 (21) Application number: 12720898.1 (22) Date of filing: 16.05.2012

(51) International Patent Classification (IPC):  A61K 45/00(2006.01) A61K 39/395(2006.01) (86) International application number: PCT/EP2012/059098 (87) International publication number: WO 2012/156437 (22.11.2012 Gazette 2012/47)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 17.05.2011 EP 11166446 (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim am Rhein (DE)	(72) Inventors: DENIS, Louis 55216 Ingelheim Am Rhein (DE) LORENCE, Robert RIdgefield Connecticut 06877 (US) SHAHIDI, Mehdi 55216 Ingelheim Am Rhein (DE) SOLCA, Flavio 55216 Ingelheim Am Rhein (DE) (74) Representative: Simon, Elke Anna Maria et al Boehringer Ingelheim GmbH Corporate Patents Binger Strasse 173 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)