(19)

(11)

EP 2 714 080 A1

(12)

(43) Date of publication: 09.04.2014 Bulletin 2014/15 (21) Application number: 12789521.7 (22) Date of filing: 23.05.2012

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61K 39/00(2006.01) (86) International application number: PCT/US2012/039098 (87) International publication number: WO 2012/162367 (29.11.2012 Gazette 2012/48)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 25.05.2011 US 201161489949 P (71) Applicant: MedImmune, LLC Gaithersburg, MD 20878 (US)

(72) Inventors: CRISTE, Ryan Gaithersburg, MD 20878 (US) ROSKOS, Lorin Gaithersburg, MD 20878 (US) WHITE, Wendy Gaithersburg, MD 20878 (US) ETHGEN, Dominique Gaithersburg, MD 20878 (US) NARWAL, Rajesh Gaithersburg, MD 20878 (US) ROBBIE, Gabriel Gaithersburg, MD 20878 (US) (74) Representative: Ttofi, Evangelia  MedImmune Limited Milstein Building Granta Park Cambridge Cambridgeshire CB21 6GH Cambridgeshire CB21 6GH (GB)