(19)

(11)

EP 2 717 868 A1

(12)

(43) Date of publication: 16.04.2014 Bulletin 2014/16 (21) Application number: 12725047.0 (22) Date of filing: 01.06.2012

(51) International Patent Classification (IPC):  A61K 31/138(2006.01) A61K 31/58(2006.01) A61P 11/06(2006.01) A61K 31/439(2006.01) A61K 45/06(2006.01) A61P 11/08(2006.01) (86) International application number: PCT/EP2012/060444 (87) International publication number: WO 2012/168161 (13.12.2012 Gazette 2012/50)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 08.06.2011 US 201161494600 P (71) Applicant: Glaxo Group Limited Brentford, Middlesex TW8 9GS (GB)	(72) Inventor: CRATER, Glenn Mississauga, Ontario L5N 6L4 (CA) (74) Representative: Fowler, Gavin James  GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road Brentford, Middlesex TW8 9GS Brentford, Middlesex TW8 9GS (GB)