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(11)

EP 2 718 428 A1

(12)

(43) Date of publication: 16.04.2014 Bulletin 2014/16 (21) Application number: 12801020.4 (22) Date of filing: 13.06.2012

(51) International Patent Classification (IPC):  C12N 7/01(2006.01) A61K 39/205(2006.01) C07K 14/145(2006.01) C12N 15/00(2006.01) C12N 15/82(2006.01) A01H 5/00(2006.01) A61P 31/14(2006.01) C07K 16/10(2006.01) C12N 15/47(2006.01) C12N 7/00(2006.01) (86) International application number: PCT/CA2012/000581 (87) International publication number: WO 2012/171104 (20.12.2012 Gazette 2012/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 13.06.2011 US 201161496371 P 21.12.2011 US 201161578787 P (71) Applicant: Medicago Inc. Québec, Québec G1V 3V9 (CA)	(72) Inventors: D'AOUST, Marc-Andre Quebec Quebec G1X 4N4 (CA) LAVOIE, Pierre-Olivier Quebec Quebec G1N 2I7 (CA) VEZINA, Louis-Philippe Neuville Quebec G0A 2R0 (CA) COUTURE, Manon St. Augustin de Desmaures Quebec G3C 2A5 (CA) (74) Representative: Drysdale, Douglas Standen  Harrison Goddard Foote LLP Delta House 50 West Nile Street Glasgow G1 2NP Glasgow G1 2NP (GB)