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(11)

EP 2 723 888 A1

(12)

(43) Date of publication: 30.04.2014 Bulletin 2014/18 (21) Application number: 11868033.9 (22) Date of filing: 23.06.2011

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) G01N 33/15(2006.01) (86) International application number: PCT/CN2011/076187 (87) International publication number: WO 2012/174723 (27.12.2012 Gazette 2012/52)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (71) Applicant: Chang Gung Medical Foundation Chang Gung Memorial Hospital at Keelung Keelung City 20401 (TW)	(72) Inventors: CHUNG, Wen-Hung Guishan Township Taoyuan County 333 (TW) HUNG, Shuen-Iu Guishan Township Taoyuan County 333 (TW) (74) Representative: Lang, Christian  LangPatent Anwaltskanzlei IP Law Firm Rosenheimer Strasse 139 81671 München 81671 München (DE)