(19)

(11)

EP 2 726 035 A1

(12)

(43) Date of publication: 07.05.2014 Bulletin 2014/19 (21) Application number: 12737326.4 (22) Date of filing: 22.06.2012

(51) International Patent Classification (IPC):  A61F 9/007(2006.01) A61L 27/14(2006.01) A61F 9/00(2006.01) (86) International application number: PCT/GB2012/051468 (87) International publication number: WO 2013/005004 (10.01.2013 Gazette 2013/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 02.07.2011 US 201161571615 P (71) Applicants: UCL Business Plc. London W1T 4TP (GB) Chaloupka, Karla Zurich (CH) Seifalian, Alexander London (GB)	(72) Inventors: CHALOUPKA, Karla Zurich (CH) SEIFALIAN, Alexander London Greater London (GB) KHAW, Peng London Greater London EC1V 9EL (GB) DARBYSHIRE, Arnold London Greater London W1T 4TP (GB) (74) Representative: Simons, Amanda Louise  J A Kemp 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)