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(11)

EP 2 726 464 A1

(12)

(43) Date of publication: 07.05.2014 Bulletin 2014/19 (21) Application number: 12731150.4 (22) Date of filing: 27.06.2012

(51) International Patent Classification (IPC):  C07D 231/56(2006.01) A61P 11/00(2006.01) A61P 29/00(2006.01) A61K 31/416(2006.01) A61P 17/00(2006.01) A61P 37/00(2006.01) (86) International application number: PCT/GB2012/051503 (87) International publication number: WO 2013/001294 (03.01.2013 Gazette 2013/01)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 29.06.2011 US 201161502656 P (71) Applicants: Astrazeneca AB SE-151 85 Södertälje (SE) Bayer Intellectual Property GmbH 40789 Monheim (DE)	(72) Inventors: ANDERSSON, Helena, Ingemo SE-151 85 Södertälje (SE) CONWAY, Kelly, Yvonne Macclesfield Cheshire SK10 2NA (GB) QUAYLE, Michael, John SE-431 Mölndal (SE) (74) Representative: Curran, Clair et al Ropes & Gray International LLP 5 New Street Square London EC4A 3BF London EC4A 3BF (GB)