(19)

(11)

EP 2 731 944 A1

(12)

(43) Date of publication: 21.05.2014 Bulletin 2014/21 (21) Application number: 12738619.1 (22) Date of filing: 03.07.2012

(51) International Patent Classification (IPC):  C07D 401/14(2006.01) A61P 3/10(2006.01) A61K 31/506(2006.01) (86) International application number: PCT/IB2012/053381 (87) International publication number: WO 2013/011402 (24.01.2013 Gazette 2013/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 15.07.2011 US 201161508250 P (71) Applicant: Pfizer Inc. New York, NY 10017 (US)	(72) Inventors: DAROUT, Etzer Cambridge, Massachusetts 02138 (US) GUIMARAES, Cristiano Brookline, MA 02446 (US) MASCITTI, Vincent Groton, Connecticut 06340 (US) MCCLURE, Kim F. Mystic, Connecticut 06340 (US) (74) Representative: Pfizer  European Patent Department 23-25 avenue du Docteur Lannelongue 75668 Paris Cedex 14 75668 Paris Cedex 14 (FR)