(19)

(11)

EP 2 739 650 A2

(12)

(88) Date of publication A3: 28.03.2013 (43) Date of publication: 11.06.2014 Bulletin 2014/24 (21) Application number: 12819810.8 (22) Date of filing: 01.08.2012

(51) International Patent Classification (IPC):  C07K 16/00(2006.01) A61K 39/395(2006.01) A61K 39/00(2006.01) (86) International application number: PCT/US2012/049207 (87) International publication number: WO 2013/019889 (07.02.2013 Gazette 2013/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 01.08.2011 US 201161513872 P 22.02.2012 US 201213402527 22.02.2012 WO PCT/US2012/026112 (71) Applicant: Avaxia Biologics, Inc. Lexington, MA 02421 (US)	(72) Inventors: FOX, Barbara, S. Lexington, MA 02421 (US) BOSTWICK, Eileen, F. Lexington, MA 02421 (US) TRACEY, Daniel, E. Lexington, MA 02421 (US) SCHLEHUBER, Lisa, D. Lexington, MA 02421 (US) QUESENBERRY, Michael, S. Lexington, MA 02421 (US) (74) Representative: Chapman, Paul William  Kilburn & Strode LLP 20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)