(19)

(11)

EP 2 747 749 A1

(12)

(43) Date of publication: 02.07.2014 Bulletin 2014/27 (21) Application number: 12825689.8 (22) Date of filing: 23.08.2012

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) (86) International application number: PCT/US2012/052048 (87) International publication number: WO 2013/028852 (28.02.2013 Gazette 2013/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 25.08.2011 US 201113199360 25.08.2011 US 201113199371 25.08.2011 US 201113199358 25.08.2011 US 201113199359 25.08.2011 US 201113199372 25.08.2011 US 201113199370 (71) Applicant: Elwha LLC Bellevue, Washington 98004 (US)

(72) Inventors: AIDEN, Erez Lieberman Cambridge Massachusetts 02138 (US) BAYM, Michael H. Cambridge Massachusetts 02138 (US) HOLMAN, Paul Seattle Washington 98119 (US) HYDE, Roderick A. Redmond Washington 98052 (US) JUNG, Edward K.Y. Las Vegas Nevada 89169 (US) KARE, Jordin T. Seattle Washington 98112 (US) MYHRVOLD, Nathan P. Bellevue Washington 98004 (US) WOOD, JR., Lowell L. Bellevue Washington 98004 (US) (74) Representative: Harris, Ian Richard  D Young & Co LLP 120 Holborn London EC1N 2DY London EC1N 2DY (GB)