| (84) |
Etats contractants désignés: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priorité: |
23.08.2011 FR 1157478
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| (43) |
Date de publication de la demande: |
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02.07.2014 Bulletin 2014/27 |
| (73) |
Titulaires: |
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- Université Grenoble Alpes
38400 Saint Martin d'Hères (FR)
- Centre Hospitalier Universitaire de Grenoble
38700 La Tronche (FR)
- Vrije Universiteit Brussel
1050 Brussel (BE)
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| (72) |
Inventeurs: |
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- GHEZZI, Catherine
F-38000 Grenoble (FR)
- FAGRET, Daniel
F-38000 Grenoble (FR)
- BROISAT, Alexis
F-38000 Grenoble (FR)
- DEVOOGDT, Nick
B-1980 Zemst (BE)
- LAHOUTTE, Tony
B-1083 Ganshoren (BE)
- MUYDERMANS, Serge
B-1560 Hoeilaart (BE)
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| (74) |
Mandataire: Lavoix |
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2, place d'Estienne d'Orves
75441 Paris Cedex 09
75441 Paris Cedex 09 (FR) |
| (56) |
Documents cités: :
EP-A1- 2 206 726
FR-A1- 2 876 033
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EP-A2- 1 520 588
FR-A1- 2 914 304
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- ILSE VANEYCKEN ET AL: "Immuno-imaging using nanobodies", CURRENT OPINION IN BIOTECHNOLOGY,
vol. 22, no. 6, décembre 2011 (2011-12), pages 877-881, XP055021086, ISSN: 0958-1669,
DOI: 10.1016/j.copbio.2011.06.009
- BROISAT A ET AL: "Molecular imaging of vascular cell adhesion molecule-1 expression
in experimental atherosclerotic plaques with radiolabelled B2702-p", EUROPEAN JOURNAL
OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, SPRINGER, BERLIN, DE, vol. 34, no. 6, 12
janvier 2007 (2007-01-12), pages 830-840, XP019514008, ISSN: 1619-7089, DOI: 10.1007/S00259-006-0310-4
cité dans la demande
- DIMASTROMATTEO J ET AL: "A030 In vivo molecular imaging of vascular cell adhesion
molecule-1 expression in atherosclerotic plaques", ARCHIVES OF CARDIOVASCULAR DISEASE,
ELSEVIER, AMSTERDAM, NL, vol. 102, 1 mars 2009 (2009-03-01), page S17, XP026054546,
ISSN: 1875-2136, DOI: 10.1016/S1875-2136(09)72163-1 [extrait le 2009-03-01]
- L. M. RIOU ET AL: "Pre-Clinical and Clinical Evaluation of Nuclear Tracers for the
Molecular Imaging of Vulnerable Atherosclerosis: An Overview", CURRENT MEDICINAL CHEMISTRY,
vol. 16, no. 12, 1 avril 2009 (2009-04-01) , pages 1499-1511, XP055021246, ISSN: 0929-8673,
DOI: 10.2174/092986709787909596 cité dans la demande
- B. A. KAUFMANN ET AL: "Molecular Imaging of Inflammation in Atherosclerosis With Targeted
Ultrasound Detection of Vascular Cell Adhesion Molecule-1", CIRCULATION, vol. 116,
no. 3, 17 juillet 2007 (2007-07-17), pages 276-284, XP055020746, ISSN: 0009-7322,
DOI: 10.1161/CIRCULATIONAHA.106.684738
- C. Z. BEHM ET AL: "Molecular Imaging of Endothelial Vascular Cell Adhesion Molecule-1
Expression and Inflammatory Cell Recruitment During Vasculogenesis and Ischemia-Mediated
Arteriogenesis", CIRCULATION, vol. 117, no. 22, 1 juin 2008 (2008-06-01) , pages 2902-2911,
XP055020750, ISSN: 0009-7322, DOI: 10.1161/CIRCULATIONAHA.107.744037
- MATTHIAS NAHRENDORF ET AL: "Noninvasive vascular cell adhesion molecule-1 imaging
identifies inflammatory activation of cells in atherosclerosis", CIRCULATION, LIPPINCOTT
WILLIAMS & WILKINS, US, vol. 114, no. 14, 1 octobre 2006 (2006-10-01), pages 1504-1511,
XP002639504, ISSN: 0009-7322, DOI: 10.1161/CIRCULATIONAHA.106.646380
- KELLY K A ET AL: "Detection of Vascular Adhesion Molecule-1 Expression Using a Neovel
Multimodal Nanoparticle", CIRCULATION RESEARCH, GRUNE AND STRATTON, BALTIMORE, US,
vol. 96, 18 février 2005 (2005-02-18), pages 327-336, XP002456858, ISSN: 0009-7330,
DOI: 10.1161/01.RES.0000155722.17881.DD
- BROISAT A ET AL: "Imagerie moleculaire de la plaque d'atherome vulnerable. Evaluation
preclinique et clinique de traceurs radioactifs", MEDECINE NUCLEAIRE, ELSEVIER, PARIS,
FR, vol. 33, no. 3, 1 mars 2009 (2009-03-01), pages 128-136, XP025968615, ISSN: 0928-1258,
DOI: 10.1016/J.MEDNUC.2009.01.004 [extrait le 2009-02-25]
- DE GROEVE KURT ET AL: "Nanobodies as tools for in vivo imaging of specific immune
cell types", JOURNAL OF NUCLEAR MEDICINE, SOCIETY OF NUCLEAR MEDICINE, RESTON, VA,
US, vol. 51, no. 5, 1 mai 2010 (2010-05-01), pages 782-789, XP009152829, ISSN: 0161-5505
- SOPHIE HERNOT ET AL: "Nanobody-coupled microbubbles as novel molecular tracer", JOURNAL
OF CONTROLLED RELEASE, vol. 158, no. 2, 1 mars 2012 (2012-03-01), pages 346-353, XP055020683,
ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2011.12.007
- A. BROISAT ET AL: "Nanobodies Targeting Mouse/Human VCAM1 for the Nuclear Imaging
of Atherosclerotic Lesions", CIRCULATION RESEARCH, vol. 110, no. 7, 30 mars 2012 (2012-03-30)
, pages 927-937, XP55041152, ISSN: 0009-7330, DOI: 10.1161/CIRCRESAHA.112.265140
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