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EP 2 755 630 A2

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(88) Date of publication A3: 13.03.2014 (43) Date of publication: 23.07.2014 Bulletin 2014/30 (21) Application number: 12769798.5 (22) Date of filing: 13.09.2012

(51) International Patent Classification (IPC):  A61K 8/73(2006.01) A61K 8/67(2006.01) A61L 27/50(2006.01) A61K 47/48(2006.01) A61Q 19/08(2006.01) A61L 27/20(2006.01) C08B 37/08(2006.01) (86) International application number: PCT/US2012/055211 (87) International publication number: WO 2013/040242 (21.03.2013 Gazette 2013/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 14.09.2011 US 201161534780 P 23.08.2012 WO PCT/US2012/052125 (71) Applicants: Allergan, Inc. Irvine, CA 92612 (US) Paliwal, Sumit Goleta, California 93117 (US)	(72) Inventors: PALIWAL, Sumit Goleta, California 93117 (US) NJIKANG, Gabriel N. Orcutt, California 93455 (US) YU, Xiaojie Irvine, California 92602 (US) LIU, Futian Sunnyvale, California 94087 (US) MANESIS, Nicholas J. Summerland, California 93067 (US) (74) Representative: HOFFMANN EITLE  Patent- und Rechtsanwälte Arabellastrasse 4 81925 München 81925 München (DE)