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EP 2 755 685 A1

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(43) Date of publication: 23.07.2014 Bulletin 2014/30 (21) Application number: 11872271.9 (22) Date of filing: 12.09.2011

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) (86) International application number: PCT/US2011/051202 (87) International publication number: WO 2013/039471 (21.03.2013 Gazette 2013/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (71) Applicant: Janssen Biotech, Inc. Horsham, PA 19044 (US)

(72) Inventors: CUNNINGHAM, Mark Spring House, PA 19477 (US) FENG, Yiqing Spring House, PA 19477 (US) HEERINGA, Katharine Spring House, PA 19477 (US) LUO, Jinquan Spring House, PA 19477 (US) RAUCHENBERGER, Robert 82490 Martinsried (DE) RUTZ, Mark 82490 Martinsried (DE) SAN MATEO, Lani Spring House, PA 19477 (US) SARISKY, Robert Lansdale, PA 19446 (US) STOJANOVIC-SUSULIC, Vedrana Spring House, PA 19477 (US) SWEET, Raymond Spring House, PA 19477 (US) TENG, Fang Spring House, PA 19477 (US) TEPLYAKOV, Alexey Spring House, PA 19477 (US) WU, Linda Spring House, PA 19477 (US) WU, Sheng-Jiun Spring House, PA 19477 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)