(19)
(11) EP 2 755 986 A1

(12)

(43) Date of publication:
23.07.2014 Bulletin 2014/30

(21) Application number: 12831509.0

(22) Date of filing: 11.09.2012
(51) International Patent Classification (IPC): 
C07H 21/02(2006.01)
A61K 48/00(2006.01)
(86) International application number:
PCT/US2012/054561
(87) International publication number:
WO 2013/039857 (21.03.2013 Gazette 2013/12)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 12.09.2011 US 201161533537 P

(71) Applicant: Moderna Therapeutics, Inc.
Cambridge, MA 02139 (US)

(72) Inventors:
  • BANCEL, Stephane
    Cambridge, Massachusetts 02139 (US)
  • SCHRUM, Jason, P.
    Philadelphia, Pennsylvania 19127 (US)
  • ARISTARKHOV, Alexander
    Chestnut Hill, MA 02467 (US)

(74) Representative: Vossius & Partner 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF