(19)

(11)

EP 2 758 438 A1

(12)

(43) Date of publication: 30.07.2014 Bulletin 2014/31 (21) Application number: 12778970.9 (22) Date of filing: 21.09.2012

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C07K 16/46(2006.01) C07K 16/30(2006.01) (86) International application number: PCT/EP2012/068673 (87) International publication number: WO 2013/041687 (28.03.2013 Gazette 2013/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 23.09.2011 US 201161538716 P (71) Applicant: Amgen Research (Munich) GmbH 81477 München (DE)	(72) Inventors: KUFER, Peter 81477 Munich (DE) KISCHEL, Roman 81477 Munich (DE) RAU, Doris 81477 Munich (DE) RAUM, Tobias 81477 Munich (DE) LUTTERBUESE, Ralf 81477 Munich (DE) HOFFMANN, Patrick 81477 Munich (DE) (74) Representative: Schiweck, Weinzierl & Koch  European Patent Attorneys Landsberger Straße 98 80339 München 80339 München (DE)