(19)

(11)

EP 2 768 896 A2

(12)

(43) Date of publication: 27.08.2014 Bulletin 2014/35 (21) Application number: 12834037.9 (22) Date of filing: 21.09.2012

(51) International Patent Classification (IPC):  C08K 3/00(2006.01) (86) International application number: PCT/US2012/056641 (87) International publication number: WO 2013/044078 (28.03.2013 Gazette 2013/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 23.09.2011 US 201161538223 P (71) Applicant: University of Massachusetts Medical School Boston, MA 02110 (US)	(72) Inventors: SONG, Jie Shrewsbury, MA 01545 (US) KUTIKOV, Artem Worcester, MA 01606 (US) (74) Representative: Aechter, Bernd  Ter Meer Steinmeister & Partner Mauerkircherstraße 45 81679 München 81679 München (DE)