TECHNICAL FIELD
[0001] The present invention relates to a container for centrifugal separator which separates
materials having different components or specific gravities by centrifugal force.
BACKGROUND ART
[0002] Blood, which is liquid tissue flowing in blood vessels, is broadly divided into blood
cell and blood plasma. The blood cell consists of red blood cell, white blood cell
and platelet, and the blood plasma mainly consisting of water includes blood coagulation
factor and electrolyte which are essential for life conservation.
[0003] At present day, various methods are used for separating ingredients of the blood
and extracting each ingredient of the blood for medical purpose. Furthermore, as a
device for separating the ingredients of the blood, a centrifugal separator is used
which utilizes the centrifugal force.
[0004] More specifically, when precipitation occurs after sampled blood is injected into
the container and the container is placed in the centrifugal separator and then rotated
at a predetermined rotational speed, ingredients of the blood are separated due to
difference in specific gravity. That is to say, heavier blood cells form a layer in
a lower part, lighter blood plasma forms a layer in an upper part, and a buffy coat
layer making up about 1% of the blood is formed between the blood cells and blood
plasma.
[0005] Collected in the buffy coat layer are a majority of PRP(Platelet Rich Plasma) which
contains stem cells that promote cell proliferation, growth of epithelial cells, revascularization,
production of collagen, production of hyaluronic acid and wound healing etc..
[0006] Accordingly, a container for centrifugal separator is required which can extract
the buffy coat layer without loss.
[0007] With reference to Fig. 1, description will be made of a container for centrifugal
separator of related art used for extracting buffy coat layer of the blood.
[0008] As illustrated in Fig. 1, a container for centrifugal separator (10) includes a pipe-shaped
body (11) with an open top end and a cap (15) sealingly coupled with the top end of
the body (11).
[0009] The body (11) has a lower receiving portion (11a), an upper receiving portion (11b)
formed with a diameter approximately identical to that of the lower receiving portion
(11a), and a connection portion (11c) connecting the lower receiving portion (11a)
and the upper receiving portion (11b). At this time, the connection portion (11c)
is formed to have a smaller diameter than those of the lower receiving portion (11a)
and the upper receiving portion (11b).
[0010] Therefore, the blood cells are received in the lower receiving portion (11a), the
blood plasma is received in the upper receiving portion (11b), and the buffy coat
layer is received in the connection portion (11c), when precipitation occurs after
sampled blood is injected into the container (10) and the container (10) is placed
in a centrifugal separator (not illustrated) to be rotated at a predetermined rotational
speed.
[0011] Subsequently, the buffy coat layer is sampled by extracting the buffy coat layer
in such a tornado manner that a syringe needle (not illustrated) is rotated round
and round while the needle is positioned in the buffy coat layer. That is, the buffy
coat layer can be easily extracted and sampled only in a case where the buffy coat
layer is positioned in the connection portion (11c) when the blood has been centrifuged
in the container (10).
[0012] By the way, when the blood has been centrifuged, the buffy coat layer may be positioned
in the lower receiving portion (11a) or in the upper receiving portion (11b) depending
on the amount of blood etc.. In a case where the buffy coat layer is positioned in
the lower receiving portion (11a), the blood is further injected into the lower receiving
portion (11a) by the use of the syringe, and in a case where the buffy coat layer
is positioned in the upper receiving portion (11b), the blood cells received in the
lower receiving portion (11a) are removed by the used of the syringe, and thereafter
the centrifugation is performed again.
[0013] The conventional container for centrifugal separator (10) as described above has
no means for adjusting a position of the buffy coat layer when the buffy coat layer
is positioned in the lower receiving portion (11a) or upper receiving portion (11b),
and thus has a disadvantage of being inconvenient in that the blood has to be further
injected or the blood cells have to be removed by the used of the syringe.
[0014] A container for centrifugal separator which solves such a problem is disclosed in
Korean Laid-Open Publication No.
10-2011-0080245 entitled "integrated separation device".
[0015] The integrated separation device (1) includes a first lower chamber (10), a second
upper chamber (20), a connection neck (30) for connecting the first chamber (10) and
the second chamber (20), and a lower cover (40) coupled with a lower end portion of
the first chamber (10).
[0016] Furthermore, the lower cover (40) has a lower cap (41) coupled with the first chamber
(10) and having an adjustment hole formed at a center of the lower cap, an adjustment
plate (42) positioned within the lower cap (41) to close the adjustment hole, and
an adjustment piece (43) upward-downward movably coupled with an inner circumferential
surface of the lower cap (41) and positioned below the adjustment plate (42). Thus,
by adjusting a position of the adjustment piece (43) coupled with the lower cap (41),
internal volume of the first chamber (10) is adjusted, thereby adjusting the position
of the buffy coat layer.
[0017] By the way, the conventional integrated separation device as described above may
be damaged when it is rotated while being placed in the centrifugal separator(not
illustrated).
[0018] More specifically, as illustrated in Fig. 2, the integrated separation device (1)
is directly inserted in an insertion hole formed in the centrifugal separator and
then rotated, or is directly inserted in the insertion hole of the centrifugal separator
and then rotated through a cylindrical bucket (2) having an open top end. By the way,
when the adjustment piece (43) of the lower cover (40)refer to the Korean Laid-Open
Publication) is lowered beyond a predetermined location, the connection neck (30)
is positioned outside the insertion hole of the centrifugal separator or outside the
bucket (2).
[0019] Then, an outer circumferential surface of the connection neck (30) is not supported
on an inner circumferential surface of the insertion hole of the centrifugal separator
or an inner circumferential surface of the bucket (2). Therefore, in rotation of the
centrifugal separator, the integrated separation device (1) exposed outside the insertion
hole of the centrifugal separator or outside the bucket (2) may radially move and
thus be damaged.
[0020] Although formed on the outer circumferential surface of the connection neck (30)
is an approximately arc-shape reinforcing rib (70) that is concave toward the inside
of the connection neck (30), the reinforcing rib (70) is also not supported on the
inner circumferential surface of the insertion hole of the centrifugal separator or
the inner circumferential surface of the bucket (2). Therefore, in rotation of the
centrifugal separator, the integrated separation device (1) is not prevented from
moving.
SUMMARY OF THE INVENTION
Technical Problem
[0021] The present invention was made in order to solve the problems as described above,
and its objects is to provide a container for centrifugal separator wherein the container
with blood injected thereinto can be prevented from being damaged in rotation of the
centrifugal separator by configuring the container such that an outer circumferential
surface of the container always contacts with an inner circumferential surface of
the bucket or an inner circumferential surface of an insertion hole of the centrifugal
separator.
Solution to Problem
[0022] For achieving the above-mentioned object, a container for centrifugal separator according
to present invention is directly inserted and supported in an insertion hole formed
in a centrifugal separator or is inserted and supported in the insertion hole through
a bucket, a mixture where materials having different specific gravities and components
are mixed is injected into the container, and the mixture is separated by centrifugal
force when the container is rotated by the centrifugal separator, and the container
comprises a pipe-shaped body having a lower receiving portion, an upper receiving
portion positioned above the lower receiving portion, and a connection portion formed
to have a smaller diameter than those of the lower receiving portion and the upper
receiving portion and connecting the lower receiving portion and the upper receiving
portion, the mixture being injected into the body; a lower cover which is coupled
with an outer circumferential surface of the lower receiving portion so that the cover
can be raised and lowered and which opens and closes an open lower end of the lower
receiving portion and which adjusts the height of the mixture injected into the body,
with a lower end portion of the body taken as a reference; and a plurality of supporting
ribs which are formed on an outer circumferential surface of the connection portion
and which contact with an inner circumferential surface of the insertion hole or an
inner circumferential surface of the bucket.
Effects of the Invention
[0023] In the container for centrifugal separator according to the present invention, even
when the lower cover coupled with the lower receiving portion of the body is lowered
beyond a predetermined location, the supporting ribs formed on the connection portion
contacts with the inner circumferential surface of the insertion hole of the centrifugal
separator in which the container is inserted and supported or with the inner circumferential
surface of the bucket. Then, the container cannot radially move even when the centrifugal
separator rotates, and thus the container is prevented from being damaged.
BRIEF DESCRIPTION OF THE DRAWINGS
[0024]
Fig. 1 is a perspective view of a conventional container for centrifugal separator;
Fig. 2 is a perspective view of another conventional container for centrifugal separator;
Fig. 3 is a perspective view of a container for centrifugal separator according to
an embodiment of the present invention;
Fig. 4 is an exploded perspective view of Fig. 3; and
Fig. 5 is a sectional view of Fig. 3.
<list of reference numerals>
[0025]
110: body
111: lower receiving portion
114: upper receiving portion
117: connection portion
120: lower cover
130: upper cover
150: supporting rib
BEST MODE FOR CARRYING OUT THE INVENTION
[0026] Detailed description of the present invention described later refers to the attached
drawings illustrating by way of example particular embodiments according to which
the present invention can be implemented. It should be appreciated that various embodiments
of the present invention are different from one another, however, need not to be mutually
exclusive. For example, specific shapes, specific structures and characteristics described
in one embodiment can be realized in another embodiment without the spirit and scope
of the present invention. Furthermore, it should be appreciated that positions or
arrangement of individual constituent elements in each embodiment disclosed may be
altered without departing from the gist and scope of the present invention. Therefore,
detailed description described later is not intended to be restrictive, and the scope
of the present invention is limited by appended claims and its equivalent, if properly
described. Length, area, thickness and form in embodiments illustrated in the drawings
may be exaggerated for the sake of convenience.
[0027] Hereinafter, a container for centrifugal separator according to an embodiment of
the present invention will be described in detail with reference to the attached drawings.
[0028] Fig. 3 is a perspective view of a container for centrifugal separator according to
an embodiment of the present invention, Fig. 4 is an exploded perspective view of
Fig. 3, and Fig. 5 is a sectional view of Fig. 3.
[0029] As illustrated in the figures, the container for centrifugal separator (100) according
to the present embodiment includes a body (110), a lower cover (120) and an upper
cover (130). The container (100) is directly inserted and supported in an insertion
hole formed in the centrifugal separator(not illustrated), or is inserted and supported
in the insertion hole of the centrifugal separator through a bucket (50) (refer to
Fig. 5). Injected into the container (100) is a mixture, such as blood, where materials
having different specific gravities and components are mixed, and when the container
(100) is rotated by the centrifugal separator, the mixed materials are separated by
centrifugal force.
[0030] The body (110) is formed in the form of pipe with open upper and lower ends, and
has a lower receiving portion (111), an upper receiving portion (114) positioned above
the lower receiving portion (111), and a connection portion (117) formed between the
lower receiving portion (111) and the upper receiving portion (114) to connect the
lower receiving portion (111) and the upper receiving portion (114). At this time,
the connection portion (117) is formed to have a smaller diameter than those of the
lower receiving portion (111) and the upper receiving portion (111).
[0031] A lower cover (120) is coupled with an outer circumferential surface of the lower
receiving portion (111), and opens and closes an open lower end of the body (110),
i.e., an open lower end of the lower receiving portion (111). At this time, the lower
cover (120) is coupled with the lower receiving portion (111) such that the cover
can be raised and lowered. Therefore, by adjusting a position of the lower cover (120)
coupled with the lower receiving portion (111), the height of the mixture injected
into the body (110) is adjusted, with the lower end portion of the body (110) taken
as a reference.
[0032] Spiral portions (111a, 121) engaging each other are formed on the outer circumferential
surface of the lower receiving portion (111) and an inner circumferential surface
of the lower cover (120), respectively so that the lower cover (120) coupled with
the outer circumferential surface of the lower receiving portion (111) can be raised
and lowered. Therefore, the lower cover (120) is raised or lowered along the lower
receiving portion (111) as the lower cover (120) is rotated in forward or reverse
direction with respective to the lower receiving portion (111).
[0033] A plurality of protruding rails (123) are formed on an outer circumferential surface
of the lower cover (120). The protruding rails (123) prevent a user's hand from slipping
when the user holds and rotates the lower cover (120) by his/her hand.
[0034] Arranged on the outer circumferential surface of the lower receiving portion (111)
is a sealing member (141), such as O-ring, which provides seal between the lower receiving
portion (111) and the lower cover (120). Furthermore, formed on the outer circumferential
surface of the lower receiving portion (111) is a ring-shaped seating groove (111b)
in which the sealing member (141) is inserted and seated (refer to Fig. 5). Since
the sealing member (141) is inserted and seated in the seating groove (111b), the
sealing member (141) is prevented from being raised or lowered due to the raising
or lowering of the lower cover (120).
[0035] The upper cover (130) is coupled with an outer circumferential surface of the upper
receiving portion (114), and opens and closes an open upper end of the body (110),
i.e., an open upper end of the upper receiving portion (114).
[0036] Also arranged on the outer circumferential surface of the upper receiving portion
(114) is a sealing member (145), such as O-ring, which provides seal between the upper
receiving portion (114) and the upper cover (130). Furthermore, formed on the outer
circumferential surface of the upper receiving portion (114) is a catch rim (114a)
for preventing the sealing member (145), which is pressed downward from above by the
upper cover (130), from deviating toward a lower side of the upper receiving portion
(114).
[0037] A catch shoulder (131) formed on an inner circumferential surface of the upper cover
(130) is caught on a lower surface of the catch rim (114a) (refer to Fig. 5). The
catch rim (114a) and the catch shoulder (131) prevent the upper cover (130) from deviating
from the upper receiving portion (114).
[0038] The body (110) is formed from transparent material so that the mixture can be observed
from the outside, and graduations (110a) indicating the amount of the mixture may
be marked on the outer circumferential surface of the body (110).
[0039] A method for using the container (100) according to the present embodiment will be
described, taking the blood for example.
[0040] With the body (110) closed by the lower cover (120 and the upper cover (130), sampled
blood is injected into the body (110) by the use of the syringe etc., and the container
(100) is placed in the centrifugal separator and then rotated at a predetermined rotational
speed, and thereafter precipitation occurs.
[0041] Then, heavier blood cells form a layer in the lower receiving portion (111), lighter
blood plasma forms a layer in the upper receiving portion (114), and the buffy coat
layer formed between the blood cells and the blood plasma is positioned in the connection
portion (117). Therefore, the buffy coat layer positioned in the connection portion
(117) can be extracted in a tornado manner.
[0042] By the way, the buffy coat layer may not be positioned in the connection portion
(117), depending on the amount of blood initially injected etc.. When the buffy coat
layer is positioned in the lower receiving portion (111), the lower cover (120) is
rotated in the forward direction to be raised, whereby the buffy coat layer is positioned
in the connection portion (117), and in such a state, the centrifugation is performed
again. Also, when the buffy coat layer is positioned in the upper receiving portion
(114), the lower cover (120) is rotated in the reverse direction to be lowered, whereby
the buffy coat layer is positioned in the connection portion (117), and in such a
state, the centrifugation is performed again.
[0043] By the way, when the body (100) is inserted in the insertion hole of the centrifugal
separator or in the bucket (50) with the lower cover (120) lowered beyond the predetermined
location, the connection portion (117) is positioned outside the insertion hole of
the centrifugal separator or outside the bucket (50). Then, a space between an inner
circumferential surface of the insertion hole of the centrifugal separator and an
outer circumferential surface of the connection portion (117) or a space between an
inner circumferential surface of the bucket (50) and the outer circumferential surface
of the connection portion (117) is widened, and thus the container (100) may radially
move due to rotation of the centrifugal separator and thus be damaged.
[0044] For preventing this, the container for centrifugal separator (100) according to the
present embodiment is formed with a plurality of supporting ribs (150).
[0045] More specifically, on the outer circumferential surface of the connection portion
(117), the plurality of supporting ribs (150)are formed along a longitudinal direction
of the body (110) and radially with respect to a center of the body (110). The supporting
ribs (150) contact with the inner circumferential surface of the insertion hole of
the centrifugal separator or the inner circumferential surface of the bucket (50).
[0046] Then, even when the lower cover (120) is lowered beyond the predetermined location,
the container (100) is prevented from radially moving, since the supporting ribs (150)
contact with the inner circumferential surface of the insertion hole of the centrifugal
separator or the inner circumferential surface of the bucket (50). Thus, the container
(100) is prevented from being damaged.
[0047] Reference numeral "133"(not described) in Figs. 3 to 5 designates a soft membrane
for insertion of the syringe needle.
[0048] The drawings for the embodiment of the present invention described above is schematically
shown such that parts associated with the technical concepts of the present invention
can be easily understood, with detailed outlines omitted. Furthermore, the above-described
embodiment is cannot be a basis for limiting the technical concepts of the present
invention, rather is only a reference for understanding technical matters included
in the claims of the present invention.
1. A container for centrifugal separator, wherein the container is directly inserted
and supported in an insertion hole formed in a centrifugal separator or is inserted
and supported in the insertion hole through a bucket, a mixture where materials having
different specific gravities and components are mixed is injected into the container,
and the mixture is separated by centrifugal force when the container is rotated by
the centrifugal separator, and
the container comprising:
a pipe-shaped body having a lower receiving portion, an upper receiving portion positioned
above the lower receiving portion, and a connection portion formed to have a smaller
diameter than those of the lower receiving portion and the upper receiving portion
and connecting the lower receiving portion and the upper receiving portion, the mixture
being injected into the body;
a lower cover which is coupled with an outer circumferential surface of the lower
receiving portion so that the cover can be raised and lowered and which opens and
closes an open lower end of the lower receiving portion and which adjusts the height
of the mixture injected into the body, with a lower end portion of the body taken
as a reference; and
a plurality of supporting ribs which are formed on an outer circumferential surface
of the connection portion and which contact with an inner circumferential surface
of the insertion hole or an inner circumferential surface of the bucket.
2. The container for centrifugal separator according to claim 1, wherein an upper end
of the upper receiving portion is open, and an upper cover is coupled with an outer
circumferential surface of the upper receiving portion, the upper cover opening and
closing the upper end of the upper receiving portion.
3. The container for centrifugal separator according to claim 1, wherein a sealing member
is arranged on the outer circumferential surface of the lower receiving portion for
providing seal between the lower receiving portion and the lower cover.
4. The container for centrifugal separator according to claim 3, wherein formed on the
outer circumferential surface of the lower receiving portion is a ring-shaped seating
groove in which the sealing member is inserted and seated.
5. The container for centrifugal separator according to claim 2, wherein provided on
the outer circumferential surface of the upper receiving portion is a sealing member
for providing seal between the upper receiving portion and the upper cover.
6. The container for centrifugal separator according to claim 5, wherein formed on the
outer circumferential surface of the upper receiving portion is a catch rim for preventing
the sealing member from deviating toward a lower side of the upper receiving portion.
7. The container for centrifugal separator according to claim 6, wherein formed on an
inner circumferential surface of the upper cover is a catch shoulder which is caught
on the catch rim.
8. The container for centrifugal separator according to claim 1, wherein spiral portions
engaging each other are formed on the outer circumferential surface of the lower receiving
portion and an inner circumferential surface of the lower cover, respectively.
9. The container for centrifugal separator according to claim 8, wherein a plurality
of protruding rails are formed on an outer circumferential surface of the lower cover.
10. The container for centrifugal separator according to any one claims 1 to 9, wherein
the body is formed of transparent material, and graduations are marked on an outer
circumferential surface of the body.