(19)
(11) EP 2 783 685 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
08.11.2017 Bulletin 2017/45

(45) Mention of the grant of the patent:
04.10.2017 Bulletin 2017/40

(21) Application number: 12850864.5

(22) Date of filing: 24.04.2012
(51) International Patent Classification (IPC): 
A61K 31/4015(2006.01)
A61P 25/00(2006.01)
(86) International application number:
PCT/CN2012/074576
(87) International publication number:
WO 2013/075459 (30.05.2013 Gazette 2013/22)

(54)

USE OF LEVO-OXIRACETAM IN PREPARATION OF MEDICINES FOR PREVENTING OR TREATING COMA

VERWENDUNG VON LEVO-OXIRACETAM BEI DER HERSTELLUNG VON ARZNEIMITTELN ZUR PROPHYLAXE ODER BEHANDLUNG VON KOMA

UTILISATION DE LÉVO-OXIRACÉTAM POUR LA PRÉPARATION DE MÉDICAMENTS POUR LA PRÉVENTION OU LE TRAITEMENT DU COMA


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 23.11.2011 CN 201110376607

(43) Date of publication of application:
01.10.2014 Bulletin 2014/40

(73) Proprietor: CHONGQING RUZER PHARMACEUTICAL CO., LTD.
Yubei District Chongqing 401120 (CN)

(72) Inventor:
  • YE, Lei
    Yubei Chongqing 401120 (CN)

(74) Representative: Abel & Imray 
Westpoint Building James Street West
Bath BA1 2DA
Bath BA1 2DA (GB)


(56) References cited: : 
WO-A1-2011/120281
CN-A- 101 766 597
CN-A- 101 396 358
CN-A- 102 204 904
   
  • ZHANG ET AL: "The neuroelectriphysiological study of the effects of oxiracetam treating the mild and moderate traumatic brain injury", 1 May 2005 (2005-05-01), MASTER THESIS, CN, PAGE(S) 46PP, XP008173737, * abstract * * page 38, line 11 *
  • M. H. Beers, R. Berkow: "The Mecrk Manual of Diagnosis and Therapy, Seventeenth Edition", 1999, Merch Research Laboratories, Whitehouse Station N.J., XP002735898, pages 1385-1389, * page 1386; tables 170-1 * * page 1387; tables 170-2 *
  • SCHVARTSMAN ET AL: "[Effectiveness of piracetam in the treatment of toxic coma ]. EFFICACITE DU PIRACETAM DANS LE TRAITEMENT DES COMAS TOXIQUES", RIVISTA DI TOSSICOLOGIA, SPERIMENTALE E CLINICA : RASSEGNA BIMESTRALE DI TOSSICOLOGIA DEL CENTRO NAZIONALE CONTRO LE INTOSSICAZIONI, SOCIET GBP A EDITRICE UNIVERSO, IT, vol. 7, no. 1-2, 1 January 1977 (1977-01-01), pages 9-11, XP008174845, ISSN: 0390-6019
  • CALLIAUW L ET AL: "Clinical trial of piracetam in disorders of consciousness due to head injury", ACTA ANAESTHESIOLOGICA BELGICA, PUBLICATIONS ACTA MEDICA BELGICA, BRUSSELS, BE, vol. 26, no. 1, 1 April 1975 (1975-04-01), pages 51-60, XP008174844, ISSN: 0001-5164
  • Voronina Tatiana: "Nootropic Drugs in Alzheimer Disease Treatment. New Pharmacological Strategies" In: E. Giacobini and R. Becker: "Alzheimer Disease: Therapeutic strategies", 1994, Springer, XP002735899, pages 265-266, * page 265, paragraph 1 *
  • ZHANG, TAO: 'The neuroelectriphysiological study of the effects of oxiracetam treating the mild and moderate traumatic brain injury' MEDICINE & PUBLIC HEALTH, CHINESE SELECTED DOCTORAL DISSERTATIONS AND MASTER'S THESES FULL-TEXT DATABASES (MASTER) 15 September 2005, pages E066 - 33, XP008173737
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).