(19)

(11)

EP 2 787 878 A1

(12)

(43) Date of publication: 15.10.2014 Bulletin 2014/42 (21) Application number: 12815801.1 (22) Date of filing: 05.12.2012

(51) International Patent Classification (IPC):  A61B 5/029(2006.01) A61B 5/087(2006.01) A61B 5/083(2006.01) A61M 16/00(2006.01) (86) International application number: PCT/IB2012/056980 (87) International publication number: WO 2013/084159 (13.06.2013 Gazette 2013/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 06.12.2011 IT RM20110650 (71) Applicant: Università Campus Bio-Medico di Roma 00128 Roma (RM) (IT)	(72) Inventors: CARASSITI, Massimiliano I-00128 Roma RM (IT) SILVESTRI, Sergio I-00128 Roma RM (IT) CECCHINI, Stefano I-73048 Nardò LE (IT) SCHENA, Emiliano I-83036 Mirabella Eclano AV (IT) (74) Representative: Papa, Elisabetta et al Società Italiana Brevetti S.p.A Piazza di Pietra, 39 00186 Roma 00186 Roma (IT)