| (84) |
Designated Contracting States: |
|
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
12.12.2011 US 201161569539 P
|
| (43) |
Date of publication of application: |
|
22.10.2014 Bulletin 2014/43 |
| (73) |
Proprietor: KemPharm Consulting Inc. |
|
Gainesville FL 32605 (US) |
|
| (72) |
Inventors: |
|
- KEM, William, Reade
Gainesville, FL 32605-3454 (US)
- SOTI, Ferenc
Gainesville, FL 32601-8521 (US)
- XING, Hong
Gainesville, FL 32605 (US)
|
| (74) |
Representative: Helbig, Christian |
|
Wagner + Helbig
Patentanwälte
Pfarrstrasse 14
80538 München
80538 München (DE) |
| (56) |
References cited: :
WO-A1-92/01688
WO-A1-2008/095944
|
WO-A1-2006/133303
WO-A2-01/23385
|
|
| |
|
|
- SLAVOV S H ET AL: "A computational study of the binding of 3-(arylidene) anabaseines
to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding
protein", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER,
PARIS, FR, vol. 45, no. 6, 1 June 2010 (2010-06-01), pages 2433-2446, XP027013913,
ISSN: 0223-5234 [retrieved on 2010-02-13]
- HASHIMOTO K ET AL: "ALPHA.7 NICOTINIC RECEPTOR AGONISTS AS POTENTIAL THERAPEUTIC DRUGS
FOR SCHIZOPHRENIA", CENTRAL NERVOUS SYSTEM AGENTS IN MEDICINAL CHEMISTRY, BENTHAM
SCIENCE PUBLISHERS LTD., BUSSUM, NL, vol. 5, no. 3, 1 January 2005 (2005-01-01) ,
pages 171-184, XP009074846, ISSN: 1871-5249
- ANTOINE TALY ET AL: "Discrimination of agonists versus antagonists of nicotinic ligands
based on docking onto AChBP structures", JOURNAL OF MOLECULAR GRAPHICS AND MODELLING,
ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 30, 22 June 2011 (2011-06-22), pages 100-109,
XP028272492, ISSN: 1093-3263, DOI: 10.1016/J.JMGM.2011.06.008 [retrieved on 2011-06-29]
- SVETOSLAV H. SLAVOV ET AL.: 'A computational study of the binding of 3-(aryl idene)
anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine
binding protein.' EUROPEAN JOURNAL OF MEDICINAL CHEMIST .Y. vol. 45, no. 6, June 2010,
pages 2433 - 2446, XP027013913
- KENJI HASHIMOTO ET AL.: 'alpha7 Nicotinic Agonists as Potential Therapeutic Drugs
for Schizophrenia.' CURRENT MEDICINAL CHEMISTRY-CENTRAL NERVOUS SYSTEM AGENTS. vol.
5, no. 3, September 2005, pages 171 - 184, XP009074846
- NATALE BELLUARDO ET AL.: 'Central nicotinic receptors, neurotrophic factors and neuroprotection.'
BEHAVIOURAL BRAIN RESEARCH. vol. 113, no. 1-2, August 2000, pages 2 1 - 34, XP055156520
- ALEXANDER HOEPPING ET AL.: 'Novel Conformationally Constrained Tropane Analo gues
by 6-endo-trig Radical Cyclization and Stille Coupling, Switch of Activity toward
the serotonin and/or Norepinephrine Transporter.' JOURNAL OF M EDICINAL CHEMISTRY.
vol. 43, no. 10, 18 May 2000, pages 2064 - 2071, XP002169501
|
|
