ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................*JBDM Ver 0.1.63 (23 May 2017) - 2999001/0The file contains technical information submitted after the application was filed and not included in this specification2791135CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120180718W173deBibliographieenBibliographyfrBibliographieEP12857224.5201212112014070920160629enenen201161569539 P20111212US2018071820182920141022201443201806062018232018011220180718201829C07D 451/02 20060101AFI20150910BHEP A61K 31/46 20060101ALI20150910BHEP A61P 25/00 20060101ALI20150910BHEP deAUF NIKOTINISCHE ACETYLCHOLINREZEPTOREN GERICHTETE ANABASINDERIVATEenANABASINE DERIVATIVES TARGETING THE NICOTINIC ACETYLCHOLINE RECEPTORSfrDÉRIVÉS D'ANABASINE CIBLANT LES RÉCEPTEURS NICOTINIQUES DE L'ACÉTYLCHOLINEWO-A1-92/01688WO-A1-2006/133303WO-A1-2008/095944WO-A2-01/23385SLAVOV S H ET AL: "A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 45, no. 6, 1 June 2010 (2010-06-01), pages 2433-2446, XP027013913, ISSN: 0223-5234 [retrieved on 2010-02-13]HASHIMOTO K ET AL: "ALPHA.7 NICOTINIC RECEPTOR AGONISTS AS POTENTIAL THERAPEUTIC DRUGS FOR SCHIZOPHRENIA", CENTRAL NERVOUS SYSTEM AGENTS IN MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBLISHERS LTD., BUSSUM, NL, vol. 5, no. 3, 1 January 2005 (2005-01-01) , pages 171-184, XP009074846, ISSN: 1871-5249ANTOINE TALY ET AL: "Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures", JOURNAL OF MOLECULAR GRAPHICS AND MODELLING, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 30, 22 June 2011 (2011-06-22), pages 100-109, XP028272492, ISSN: 1093-3263, DOI: 10.1016/J.JMGM.2011.06.008 [retrieved on 2011-06-29]SVETOSLAV H. SLAVOV ET AL.: 'A computational study of the binding of 3-(aryl idene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein.' EUROPEAN JOURNAL OF MEDICINAL CHEMIST .Y. vol. 45, no. 6, June 2010, pages 2433 - 2446, XP027013913KENJI HASHIMOTO ET AL.: 'alpha7 Nicotinic Agonists as Potential Therapeutic Drugs for Schizophrenia.' CURRENT MEDICINAL CHEMISTRY-CENTRAL NERVOUS SYSTEM AGENTS. vol. 5, no. 3, September 2005, pages 171 - 184, XP009074846NATALE BELLUARDO ET AL.: 'Central nicotinic receptors, neurotrophic factors and neuroprotection.' BEHAVIOURAL BRAIN RESEARCH. vol. 113, no. 1-2, August 2000, pages 2 1 - 34, XP055156520ALEXANDER HOEPPING ET AL.: 'Novel Conformationally Constrained Tropane Analo gues by 6-endo-trig Radical Cyclization and Stille Coupling, Switch of Activity toward the serotonin and/or Norepinephrine Transporter.' JOURNAL OF M EDICINAL CHEMISTRY. vol. 43, no. 10, 18 May 2000, pages 2064 - 2071, XP00216950120150916KEM, William, Reade1809 NW 47th StreetGainesville, FL 32605-3454USSOTI, Ferenc708 SW 16th Ave. Apt. 207Gainesville, FL 32601-8521USXING, Hong2104 NW 47th PlaceGainesville, FL 32605USKemPharm Consulting Inc.101745663UF20245PCTEP1809 NW 47 StreetGainesville FL 32605USHelbig, Christian101168057Wagner + Helbig Patentanwälte Pfarrstrasse 1480538 MünchenDEALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTRUS201206894320121211enWO201309026020130620201325