(19)

(11)

EP 2 791 174 A1

(12)

(43) Date of publication: 22.10.2014 Bulletin 2014/43 (21) Application number: 12798775.8 (22) Date of filing: 12.12.2012

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) (86) International application number: PCT/EP2012/075241 (87) International publication number: WO 2013/087699 (20.06.2013 Gazette 2013/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 15.12.2011 EP 11193792 (71) Applicant: F.Hoffmann-La Roche AG 4070 Basel (CH)	(72) Inventors: FERTIG, Georg 82377 Penzberg (DE) FIDLER, Alexander 82377 Penzberg (DE) KALUZA, Klaus 82362 Weilheim (DE) RIES, Carola 82377 Penzberg (DE) SEEBER, Stefan 82404 Sindelsdorf (DE) THOMAS, Marlene 79618 Rheinfelden (DE) (74) Representative: Burger, Alexander  Roche Diagnostics GmbH Patent Department (LPP.....6164) P.O.Box 11 52 82372 Penzberg 82372 Penzberg (DE)