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(11)

EP 2 791 656 A1

(12)

(43) Date of publication: 22.10.2014 Bulletin 2014/43 (21) Application number: 12805550.6 (22) Date of filing: 06.12.2012

(51) International Patent Classification (IPC):  G01N 21/64(2006.01) C12Q 1/68(2006.01) G01N 33/58(2006.01) G01N 33/543(2006.01) G01N 33/533(2006.01) (86) International application number: PCT/US2012/068110 (87) International publication number: WO 2013/090107 (20.06.2013 Gazette 2013/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 15.12.2011 US 201113326999 (71) Applicant: Instrumentation Laboratory Company Bedford, MA 01730 (US)	(72) Inventors: LEWIS, William Beford, Massachusetts 01730 (US) FLAHERTY, James Beford, Massachusetts 01730 (US) ACHTER, Eugene K. Beford, Massachusetts 01730 (US) KUROWSKI, Dirk Beford, Massachusetts 01730 (US) (74) Representative: Evans, Claire  Fry Heath & Spence LLP The Gables Massetts Road Horley Surrey RH6 7DQ Horley Surrey RH6 7DQ (GB)