(19)

(11)

EP 2 794 633 A2

(12)

(88) Date of publication A3: 20.06.2013 (43) Date of publication: 29.10.2014 Bulletin 2014/44 (21) Application number: 12808819.2 (22) Date of filing: 20.12.2012

(51) International Patent Classification (IPC):  C07J 41/00(2006.01) C07J 75/00(2006.01) C07J 43/00(2006.01) (86) International application number: PCT/EP2012/076380 (87) International publication number: WO 2013/030410 (07.03.2013 Gazette 2013/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 23.12.2011 EP 11382399 23.12.2011 US 201161579997 P 24.02.2012 US 201261602964 P (71) Applicant: Crystal Pharma S.A.U 47151 Boecillo - Valladolid (ES)

(72) Inventors: PÉREZ ENCABO, Alfonso E-47011 Valladolid (ES) TURIEL HERNANDEZ, José Angel E-47011 Valladolid (ES) GALLO NIETO, Francisco Javier E-47151 Boecillo-Valladolid (ES) LORENTE BONDE-LARSEN, Antonio E-47151 Boecillo-Valladolid (ES) SANDOVAL RODRÍGUEZ, Celso Miguel E-47151 Boecillo-Valladolid (ES) (74) Representative: ABG Patentes, S.L.  Avenida de Burgos, 16D Edificio Euromor 28036 Madrid 28036 Madrid (ES)