(19)
(11) EP 2 796 575 A8

(12) CORRECTED EUROPEAN PATENT APPLICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 A1)

(48) Corrigendum issued on:
17.12.2014 Bulletin 2014/51

(43) Date of publication:
29.10.2014 Bulletin 2014/44

(21) Application number: 14173527.4

(22) Date of filing: 06.09.2007
(51) International Patent Classification (IPC): 
C22B 60/00(2006.01)
 C22B 3/24(2006.01)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 08.09.2006 DE 102006042191

(62) Application number of the earlier application in accordance with Art. 76 EPC:
07802184.7 / 2082071

(71) Applicant: Actinium Pharmaceuticals Inc.
Florham Park, NJ 07932 (US)

(72) Inventors:
  • Kabai, Eva
    85386 Eching (DE)
  • Moreno Bermudez, Josue Manuel
    85737 Ismaning (DE)
  • Henkelmann, Richard
    85354 Freising (DE)
  • Türler, Andreas
    85737 Ismaning (DE)

(74) Representative: Winter, Brandl, Fürniss, Hübner, Röss, Kaiser, Polte - Partnerschaft mbB 
Patent- und Rechtsanwaltskanzlei Alois-Steinecker-Strasse 22
85354 Freising
85354 Freising (DE)

 
Remarks:
This application was filed on 23-06-2014 as a divisional application to the application mentioned under INID code 62.
 


(54) Method for the purification of radium from different sources


(57) The present application is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is further related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.