(19)
(11) EP 2 796 875 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 2 (W2 B1)

(48) Corrigendum issued on:
25.11.2020 Bulletin 2020/48

(45) Mention of the grant of the patent:
27.03.2019 Bulletin 2019/13

(21) Application number: 13164922.0

(22) Date of filing: 23.04.2013
(51) International Patent Classification (IPC): 
G01N 33/574(2006.01)

(54)

Inhibitors of proteins specific for the secretome of a chondrocyte for use in the treatment of breast cancer metastasis

Hemmer von für das Sekretom eines Chondrozyts spezifischen Proteinen zur Behandlung von Brustkrebsmetastase

Inhibiteurs de protéines spécifiques de sécrétome d'un chondrocyte pour utilisation dans le traitement de la métastase du cancer du sein


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(43) Date of publication of application:
29.10.2014 Bulletin 2014/44

(73) Proprietor: Albert-Ludwigs-Universität Freiburg
79098 Freiburg (DE)

(72) Inventors:
  • Shastri, Prasad
    79112 Freiburg (DE)
  • Christensen, Jon
    79117 Freiburg (DE)

(74) Representative: Krauss, Jan 
Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22
80336 München
80336 München (DE)


(56) References cited: : 
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US-A1- 2012 172 235
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  • JENNIFER L HALPERN ET AL: "Mesenchymal stem cells promote mammary cancer cell migrationvia the CXCR2 receptor", CANCER LETTERS, NEW YORK, NY, US, vol. 308, no. 1, 28 April 2011 (2011-04-28), pages 91-99, XP028378022, ISSN: 0304-3835, DOI: 10.1016/J.CANLET.2011.04.018 [retrieved on 2011-05-02]
  • Y-L HSU ET AL: "Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/Snail signaling pathway", ONCOGENE, vol. 32, no. 37, 8 October 2012 (2012-10-08), pages 4436-4447, XP055080273, ISSN: 0950-9232, DOI: 10.1038/onc.2012.444
  • DE CEUNINCK F ET AL: "The inflammatory side of human chondrocytes unveiled by antibody microarrays", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 323, no. 3, 22 October 2004 (2004-10-22), pages 960-969, XP027194456, ISSN: 0006-291X, DOI: 10.1016/J.BBRC.2004.08.184 [retrieved on 2004-09-17]
   
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