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EP 2 797 665 A1

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(43) Date of publication: 05.11.2014 Bulletin 2014/45 (21) Application number: 12863865.7 (22) Date of filing: 28.12.2012

(51) International Patent Classification (IPC):  A61N 1/36(2006.01) A61N 1/05(2006.01) A61N 1/362(2006.01) A61B 18/18(2006.01) (86) International application number: PCT/US2012/072046 (87) International publication number: WO 2013/102062 (04.07.2013 Gazette 2013/27)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 30.12.2011 US 201161581873 P (71) Applicants: Cardialen, Inc. St. Louis, MO 63141 (US) Wessels, Richard J. St. Louis, MO 63141 (US) Efimov, Igor R. St. Louis, MO 63141 (US) Sha, Qun St. Louis, MO 63141 (US) Li, Wenwen St. Louis, MO 63141 (US)

(72) Inventors: WESSELS, Richard, J. St. Louis, MO 63141 (US) EFIMOV, Igor, R. St. Louis, MO 6314 (US) SHA, Qun St. Louis, MO 63141 (US) LI, Wenwen St. Louis, MO 63141 (US) (74) Representative: Schohe, Stefan  Boehmert & Boehmert Anwaltspartnerschaft mbB Patentanwälte Rechtsanwälte Pettenkoferstrasse 20-22 80336 München 80336 München (DE)