(19)

(11)

EP 2 804 952 A2

(12)

(88) Date of publication A3: 17.04.2014 (43) Date of publication: 26.11.2014 Bulletin 2014/48 (21) Application number: 12865606.3 (22) Date of filing: 19.01.2012

(51) International Patent Classification (IPC):  C12P 21/08(2006.01) A61K 39/00(2006.01) C07K 16/00(2006.01) (86) International application number: PCT/US2012/021888 (87) International publication number: WO 2013/109279 (25.07.2013 Gazette 2013/30)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (71) Applicant: Therapeutic Proteins International, LLC Chicago, Illinois 60616 (US)	(72) Inventor: WILTON, Rosemarie Elmhurst, Illinois 60126 (US) (74) Representative: LifeTech IP Spies Danner & Partner Patentanwälte PartG mbB  Elsenheimerstrasse 47a 80687 München 80687 München (DE)