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EP 2 807 149 A2

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(88) Date of publication A3: 31.10.2013 (43) Date of publication: 03.12.2014 Bulletin 2014/49 (21) Application number: 13722815.1 (22) Date of filing: 26.01.2013

(51) International Patent Classification (IPC):  C07D 229/02(2006.01) A61K 9/28(2006.01) A61K 31/396(2006.01) C07D 487/10(2006.01) A61P 25/00(2006.01) A61K 9/00(2006.01) A61K 9/48(2006.01) C07D 471/10(2006.01) C07D 491/107(2006.01) (86) International application number: PCT/IB2013/050682 (87) International publication number: WO 2013/111118 (01.08.2013 Gazette 2013/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR (30) Priority: 26.01.2012 US 201261591270 P (71) Applicants: CRO Consulting Limited Road Town, Tortola (VG) Makhova, Nina, N. Moscow 109651 (RU) Petukhova, Vera, Y. Moscow 127486 (RU) Shevtsov, Alexander Vladimirovich Moscow Region 142203 (RU) Novakovskiy, Vladimir, V. St. Petersburg 194356 (RU) Kuznetsov, Vladimir, Vladimirovich Moscow 140531 (RU)

(72) Inventors: MAKHOVA, Nina, N. Moscow 109651 (RU) PETUKHOVA, Vera, Y. Moscow 127486 (RU) SHEVTSOV, Alexander, V. Moscow 142203 (RU) NOVAKOVSKIY, Vladimir, V. St. Petersburg 194356 (RU) KUZNETSOV, Vladimir, Vladimirovich Moscow 140531 (RU) (74) Representative: Gilholm, Stephen Philip  IPheions Intellectual Property Buzzard Office The Hawk Creative Business Park Easingwold, York YO61 3FE Easingwold, York YO61 3FE (GB)